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Approaches of the new therapy development for atopic dermatitis by using RNA interference

Research Project

Project/Area Number 21791064
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Dermatology
Research InstitutionOsaka University (2010)
Tokyo Medical and Dental University (2009)

Principal Investigator

IGAWA Ken  Osaka University, 医学系研究科, 講師 (00372441)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
KeywordsSTAT6 / アレルギー / 治療 / RNA干渉 / 接触過敏反応
Research Abstract

Local administration of STAT6 siRNA (siRNA for STAT6) is a promising therapeutic strategy for both Th2-mediated cutaneous diseases and allergic rhinitis.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report

Research Products

(7 results)

All 2011 2010 2009

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (4 results)

  • [Journal Article] Gene silencing of STAT6 with siRNA ameliorates contact hypersensitivity and allergic rhinitis.2011

    • Author(s)
      Hosoya K, Satoh T, Yamamoto Y, Saeki K, Igawa K(10人中5番目)
    • Journal Title

      Allegy 66(1)

      Pages: 124-31

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gene silencing of STAT6 with siRNA ameliorates contact hyper sensitivity and allergic rhinitis.2011

    • Author(s)
      Hosoya K, Satoh T, Yamamoto Y, Saeki K, Igawa K, et al
    • Journal Title

      Allegy

      Volume: 66(1) Pages: 124-31

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 【アトピー性皮膚炎の正しい治療】アトピー性皮膚炎の新しい治療の展望2010

    • Author(s)
      井川健
    • Journal Title

      医薬ジャーナル 46(3)

      Pages: 994-998

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] 重症アトピー性皮膚炎の新規治療2010

    • Author(s)
      井川健
    • Organizer
      第109回日本皮膚科学会総会教育講演
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2010-04-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 重症アトピー性皮膚炎の新規治療2010

    • Author(s)
      井川健
    • Organizer
      第109回日本皮膚科学会総会教育講演
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] A therapeutic effect of STAT6 inhibition in atopic dermatitis2009

    • Author(s)
      Ken Igawa
    • Organizer
      Yonsei Cutaneous Biology Research Institute International Symposium 2009
    • Place of Presentation
      Seoul, South Korea
    • Year and Date
      2009-09-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] A therapeutic effect of ST AT6 inhibition in atopic dermatitis.2009

    • Author(s)
      Igawa K
    • Organizer
      Yonsei Cutaneous Biology Research Institute International Symposium 2009
    • Place of Presentation
      Seoul(招待講演)
    • Related Report
      2010 Final Research Report

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Published: 2009-03-31   Modified: 2016-04-21  

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