Genetic analysis of mtDNA in schizophrenia patients.
| Project/Area Number |
21791159
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | 財団法人東京都医学研究機構 (2010)
Tokyo Metropolitan Organization for Medical Research (2009) |
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Principal Investigator |
ICHIKAWA Tomoe 財団法人東京都医学研究機構, 東京都精神医学総合研究所, 研究員 (60383288)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | ミトコンドリア / 統合失調症 / 神経科学 / 脳・神経 / 脳神経疾患 |
|---|
| Research Abstract |
We searched mtDNA to detect distinctive variants using schizophrenic postmortem brains and peripheral blood samples. I found novel variants containing 2 heteroplasmic variants and disease specific non-synonymous variations which might contribute to pathophisiology of schizophrenia.
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Report
(3 results)
Research Products
(4 results)
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[Presentation] 統合失調症患者剖検脳および末梢血におけるミトコンドリアDNAの遺伝子解析2010
Author(s)
市川智恵, 新井誠, 宮下光弘, 野原泉, 小幡菜々子, 新井麻友美, 田中陽子, 大島健一, 新里和弘, 岡崎祐士, 土井永史, 糸川昌成
Organizer
第32回日本生物学的精神医学会
Place of Presentation
北九州
Year and Date
2010-10-08
Related Report
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