Imaging Oxidative Stress in Atherosclerotic plaque with Iodine-125 Labeled 4-Hydroxy-2-Nonenalin vivo

• Project/Area Number: 21791220
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: Meiji College of Oriental Medicine
• Principal Investigator: DOUE Tomoki 明治国際医療大学, 医学教育研究センター, 講師 (40411300)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 核医学 / 循環器・高血圧 / 放射線 / 酸化ストレス / 動脈硬化 / イメージング

Research Abstract

We tried to image localization of oxidative stress in atherosclerotic lesion with radiolabeled 4HNE with iodine-125. We could image oxidative stress in atherosclerotic lesion in excised aorta.

Research Products

• [Presentation] Imaging Oxidative Stress in Unstable Atherosclerotic Plaque With Iodine-125-Labeled 4-Hydroxy-2-Nonenal in vivo (2010)
  • Author(s): 堂上友紀
  • Organizer: American Heart Associatio, Scienific Session 2010
  • Place of Presentation: Chicago, USA
  • Year and Date: 2010-11-16
• [Presentation] American Heart Association Scientific Session (2010)