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Imaging of regional cerebral blood flow in the surrounding of cerebral infarction using laser speckle flowmetry system

Research Project

Project/Area Number 21791357
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Cerebral neurosurgery
Research InstitutionOsaka University

Principal Investigator

NAKAMURA Hajime  Osaka University, 医学部附属病院, 特任助教(常勤) (80533794)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords脳血管障害 / 脳虚血 / イメージング / 皮質拡延性抑制 / 局所脳血流 / レーザースペックル脳表血流計 / ラット / cortical spreading depression / peri-infarct depolarization / レーザースペックル血流計
Research Abstract

Laser speckle flowmetry, a novel non-invasive live imaging system of regional cerebral blood flow, enabled us to visualize the propagation of peri-infarct depolarization (PID) in penumbra that has not been detected with conventional imaging systems as MRI and PET. This method revealed that PID propagates not only from core to periphery in radial fashion but also along the ischemic lesion circumferentially.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (3 results)

All 2010 2009

All Presentation (3 results)

  • [Presentation] 新しい術中血流情報モニタリング~レーザースペックル脳表血流計(LSF)の臨床応用~2010

    • Author(s)
      中村元、藤中俊之、黒田淳子、西田武生、梶川隆一郎、芝野克彦、吉峰俊樹
    • Organizer
      第69回日本脳神経外科学会総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2010-10-29
    • Related Report
      2010 Final Research Report
  • [Presentation] 新しい術中血流情報モニタリング~レーザースペックル脳表血流計(LSF)の臨床応用~2010

    • Author(s)
      中村元
    • Organizer
      日本脳神経外科学会 第69回学術総会
    • Place of Presentation
      福岡コンベンションセンター福岡国際会議場
    • Year and Date
      2010-10-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] レーザースペックル血流計を用いたラット脳表血流連続モニタリング~新しい脳表血流モニタリングモデル~2009

    • Author(s)
      中村元, 藤中俊之, Anthony J Strong, Andrew K Dunn, Rudolf Graf, 吉峰俊樹
    • Organizer
      第21回日本脳循環代謝学会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2009-11-19
    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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