Imaging of regional cerebral blood flow in the surrounding of cerebral infarction using laser speckle flowmetry system
| Project/Area Number |
21791357
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Osaka University |
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Principal Investigator |
NAKAMURA Hajime Osaka University, 医学部附属病院, 特任助教(常勤) (80533794)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 脳血管障害 / 脳虚血 / イメージング / 皮質拡延性抑制 / 局所脳血流 / レーザースペックル脳表血流計 / ラット / cortical spreading depression / peri-infarct depolarization / レーザースペックル血流計 |
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| Research Abstract |
Laser speckle flowmetry, a novel non-invasive live imaging system of regional cerebral blood flow, enabled us to visualize the propagation of peri-infarct depolarization (PID) in penumbra that has not been detected with conventional imaging systems as MRI and PET. This method revealed that PID propagates not only from core to periphery in radial fashion but also along the ischemic lesion circumferentially.
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Report
(3 results)
Research Products
(3 results)
