Sevoflurane-induced postconditioning in cardiac surgery

• Project/Area Number: 21791434
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Anesthesiology/Resuscitation studies
• Research Institution: Gunma University
• Principal Investigator: KURODA Masataka Gunma University, 大学院・医学系研究科, 助教 (30375555)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 心筋保護作用 / ストレス / ポストコンディショニング / セボフルラン / 心筋トロポニン / NT-proBNP / 経食道心エコー / 心臓手術 / NT-roBNP

Research Abstract

Sevoflurane postconditioning was applied during coronary reperfusion immediately after aortic unclamping in cardiac surgery. There were no significant effects on post-operative cardiac function, inflammatory responses, and other post-operative factors.

Research Products

• [Journal Article] Preoperative depression is a risk factor for postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus. (2011)
  • Author(s): Kadoi Y, Kawauchi C, Ide M, Kuroda M, Takahashi K, Saito S, Fujita N, Mizutani A
  • Journal Title: J Anesth 25 Pages: 10-17
  • NAID: 10029021644
  • Peer Reviewed
• [Journal Article] Regurgitant leak from the area between the stent post and the sewing ring of a stented bovine pericardial valve implanted in the aortic valve position. (2010)
  • Author(s): Kuroda M, Sudo T, Koizuka S, Nishikawa K, Kadoi Y, Saito S.
  • Journal Title: Cardiovasc Ultrasound 8 Pages: 52-52
  • Peer Reviewed
• [Journal Article] Differential effects of hyperventilation on cerebral blood flow velocity after tourniquet deflation during sevoflurane, isoflurane, or propofol anesthesia. (2010)
  • Author(s): Hinohara H, Kadoi Y, Ide M, Kuroda M, Saito S, Mizutani A.
  • Journal Title: J Anesth 24 Pages: 587-593
  • NAID: 10026632724
  • Peer Reviewed
• [Journal Article] Regurgitant leak from the area between the stent post and the sewing ring of a stented bovine pericardial valve implanted in the aortic valve position. (2010)
  • Author(s): Kuroda M
  • Journal Title: Cardiovascular Ultrasound Volume: 8 Pages: 52-52
  • Peer Reviewed
• [Journal Article] Differential effects of hyperventilation on cerebral blood flow velocity after tourniquet deflation during sevoflurane, isoflurane, or propofol anesthesia. (2010)
  • Author(s): Hinohara H
  • Journal Title: Journal of Anesthesia Volume: 24 Pages: 587-593
  • Peer Reviewed
• [Journal Article] Preoperative depression is a risk factor for postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus. (2010)
  • Author(s): Kadoi Y
  • Journal Title: Journal of Anesthesia Volume: 25 Pages: 10-17
  • Peer Reviewed
• [Journal Article] Transesophageal echocardiography is useful for an intraoperative diagnosis of pulmonary artery catheter entrapment. (2009)
  • Author(s): Kuroda M, Matsuoka H, Aso C, Iriuchijima N, Miyoshi S, Kadoi Y, Saito S.
  • Journal Title: Anesth Analg 109 Pages: 1416-1418
  • Peer Reviewed
• [Journal Article] Transesophageal echocardiography is useful for intra-operative diagnosis of pulmonary artery catheter entrapment (2009)
  • Author(s): Masataka Kuroda
  • Journal Title: Anesthesia & Analgesia 109 Pages: 1416-1418
  • Peer Reviewed
• [Presentation] 肺動脈カテーテルの脱血管カニューレ縫合糸による巻き込みの術中診断に経食道心エコーが有用であった一症例 (2010)
  • Author(s): 徳江彩
  • Organizer: 日本心臓血管麻酔学会ザ・プリンス
  • Place of Presentation: パークタワー東京(東京都)
  • Year and Date: 2010-10-09
• [Presentation] 両大血管右室起始症の患者に対して腎摘出術を施行した一例 (2009)
  • Author(s): 堀内辰男、黒田昌孝、山田真紀子、入内島伸尚、齋藤繁
  • Organizer: 第29回日本臨床麻酔学会
  • Place of Presentation: アクトシティ浜松(浜松)
  • Year and Date: 2009-10-31