Innovation of prognosis and therapeutic method for complications in pregnancy using adipokine technology
Project/Area Number |
21791571
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Obstetrics and gynecology
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Research Institution | Nara Medical University |
Principal Investigator |
NARUSE Katsuhiko Nara Medical University, 医学部, 助教 (70453165)
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Project Period (FY) |
2009 – 2010
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Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 脂肪細胞 / アディポネクチン / アディポサイトカイン / 妊娠 / 妊娠糖尿病 / 妊娠高血圧症 / 絨毛細胞 |
Research Abstract |
Cytokines derived from adipocyte (adipocytokine), mainly adiponectin, were studied to clarify the effects of adipocyte on trophoblasts in normal and complicated pregnancy. The effect of free fatty acid on secretion of adiponectin was suggested in pregnancy induced hypertension. Additionally, coordinal alteration of high molecular weight adiponectin and chemokine in the course of normal pregnancy were clarified.
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Report
(3 results)
Research Products
(35 results)
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[Presentation] Correlation of free fatty acid and adiponectin in hypertensive pregnancy : key molecules for homeostatic inflammatory linkage.2010
Author(s)
Naruse K, Onogi A, Sado T, Noguchi T, Komeda S, Koyama E, Nishioka K, Kitanaka T, Oi H, Kobayashi H.
Organizer
17th World congress of the International Society for the Study of Hypertension (ISSHP).
Place of Presentation
Melbourne, Australia
Year and Date
2010-10-05
Related Report
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[Presentation] Correlation of free fatty acid and adiponectin in hypertensive pregnancy : key molecules for homeostatic inflammatory linkage.2010
Author(s)
Naruse K, Onogi A, Sado T, Noguchi T, Komeda S, Koyama E, Nishioka K, Kitanaka T, Oi H, Kobayashi H.
Organizer
17^<th> World congress of the International Society for the Study of Hypertension (ISSHP):一般演題より口演に選出
Place of Presentation
Melbourne, Australia
Year and Date
2010-10-05
Related Report
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[Presentation] Effects of Adiponectin in Differentiation, Invasion and Migration of Human Trophoblastic Cells.2009
Author(s)
Onogi A, Naruse K, Shigetomi H, Yoshizawa Y, Noguchi H, Sado T, Kitanaka T, Oi H, Kobayashi H.
Organizer
15th World Congress of International Federation of Placenta Association (IFPA).
Place of Presentation
Adelaide, Austraria
Year and Date
2009-10-06
Related Report
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[Presentation] Angiopoietin-like Protein 2 (AngPTL2) in Human Maternal Serum, Amniotic Fluid and Term Placental Trophoblast in Pregnancy.2009
Author(s)
Naruse K, Endo M, Onogi A, Shigetomi H, Yoshizawa Y, Sado T, Oi H, Oike Y, Kobayashi H.
Organizer
15th World Congress of International Federation of Placenta Association (IFPA).
Place of Presentation
Adelaide, Austraria
Year and Date
2009-10-06
Related Report
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