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Unique MicroRNA expression of Head and Neck Cancer; Analysis and Potential for Treatment Targets

Research Project

Project/Area Number 21791644
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionKeio University

Principal Investigator

INAGAKI Koji  Keio University, 医学部 (70348738)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords頭頸部外科学 / 頭頸部癌 / 癌 / 遺伝子
Research Abstract

We found specific regulations of miRNAs in head and neck cancers. To confirm these findings, we examined the effect of these miRNAs on cell growth and viability using head and neck cancer cell lines. This study showed that inhibition of miR-196a suppressed the cell growth.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report

Research Products

(10 results)

All 2010 2009 Other

All Presentation (5 results) Remarks (1 results) Patent(Industrial Property Rights) (4 results)

  • [Presentation] 頭頸部腫瘍とmiRNA(5)-新たな治療標的としてのmiRNAs-2009

    • Author(s)
      稲垣康治、齋藤康一郎、宇野光祐、小川郁、座間猛
    • Organizer
      日本気管食道科学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-11-05
    • Related Report
      2010 Final Research Report
  • [Presentation] 頭頸部腫瘍とmiRNA(5)-新たな治療標的としてのmiRNAs-2009

    • Author(s)
      稲垣康治
    • Organizer
      日本気管食道科学会
    • Place of Presentation
      横浜ベイシェラトン(横浜市)
    • Year and Date
      2009-11-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] 頭頸部癌におけるマイクロRNA2009

    • Author(s)
      宇野光祐、齋藤康一郎、稲垣康治、平沢晃、大久保啓介、座間猛
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Related Report
      2010 Final Research Report
  • [Presentation] 喉頭癌におけるマイクロRNA-3新たな治喉頭癌におけるマイクロRNA-3新たな治療標的としてのマイクロRNA2009

    • Author(s)
      稲垣康治、齋藤康一郎、長西秀樹、大久保啓介、赤羽智子、平沢晃、座間猛
    • Organizer
      日本頭頸部癌学会
    • Place of Presentation
      札幌
    • Year and Date
      2009-06-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 喉頭癌におけるマイクロRNA-3.新たな治療標的としてのマイクロRNA2009

    • Author(s)
      稲垣康治
    • Organizer
      日本頭頸部癌学会
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Year and Date
      2009-06-12
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 頭頸部腫瘍増殖抑制剤2010

    • Inventor(s)
      座間猛、齋藤康一郎、平沢晃、稲垣康治
    • Industrial Property Rights Holder
      慶應義塾大学
    • Filing Date
      2010-04-16
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 頭頸部腫瘍増殖抑制剤2010

    • Inventor(s)
      座間猛、稲垣康治, 他2名
    • Industrial Property Rights Holder
      慶應義塾大学
    • Filing Date
      2010-04-16
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 頭頸部腫瘍増殖抑制剤2009

    • Inventor(s)
      座間猛、齋藤康一郎、平沢晃、稲垣康治
    • Industrial Property Rights Holder
      慶應義塾大学
    • Industrial Property Number
      2009-270157
    • Filing Date
      2009-11-27
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 頭頸部腫瘍増殖抑制剤2009

    • Inventor(s)
      座間猛、稲垣康治, 他2名
    • Industrial Property Rights Holder
      慶應義塾大学
    • Industrial Property Number
      2009-270157
    • Filing Date
      2009-11-27
    • Related Report
      2009 Annual Research Report

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Published: 2009-03-31   Modified: 2016-04-21  

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