• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Sclerotherapy for Venous Malformations Using Infrared Fluorescence Imaging,

Research Project

Project/Area Number 21791740
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Plastic surgery
Research InstitutionThe University of Tokyo

Principal Investigator

NARUSHIMA Mitsunaga  The University of Tokyo, 医学部附属病院, 助教 (80431873)

Co-Investigator(Renkei-kenkyūsha) KOSHIMA Isao  東京大学, 医学部附属病院, 教授 (60101804)
Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords血管奇形 / 硬化療法 / インドシアニングリーン / 蛍光色素 / PDE / 治療 / photo dynamic eye / 静脈奇形 / 動静脈奇形 / 造影検査 / 近赤外線カメラ
Research Abstract

Sclerotherapy has traditionally been used with ultrasonography or angiography for the purpose of imaging venous malformations. With angiography, one can more easily visualize all structures, but through repetitive treatment there is increased exposure to radiation. Recently, a procedure using infrared light and indocyanine green dye (ICG) to detect arteries, veins, and lymphatics has been developed. By using this modality to image venous malformations, effective sclerotherapy facilitated by full imaging of the venous malformation may be possible without radiation.
In this reseach, a total of 62 patients underwent 110 sclerotherapy sessions with infrared fluorescence imaging to correct vascular malformations. As compared to digital subtraction angiography, which was performed simultaneously using mixed contrast agent injection, effective sclerotherapy of superficial malformations of the lips, palpebrae, and hands was easily confirmed with ICG imaging. We found that using ICG imaging to guide sclerotherapy for superficial venous malformations safely delivered effective and reproducible results as compared to DSA without the risk of radiation, and is applicable for broader adoption by the medical community for treating venous malformations.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (4 results)

All 2010 2009

All Presentation (4 results)

  • [Presentation] 血管奇形に対するICG/PDE下治療法とマイクロサージェリーへの応用2010

    • Author(s)
      成島三長
    • Organizer
      第37回日本マイクロサージャリー学会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 血管奇形に対する PDE下硬化療法~治療における安全性を最大限に確保するために~2010

    • Author(s)
      成島三長
    • Organizer
      第3回ICG蛍光Navigation Surgery
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] ICGガイド下硬化療法の適応2010

    • Author(s)
      成島三長
    • Organizer
      第7回血管腫血管奇形研究会
    • Place of Presentation
      愛媛
    • Year and Date
      2010-07-18
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 静脈奇形に対するインドシアニングリーンガイド下硬化療法2009

    • Author(s)
      成島三長
    • Organizer
      第52回日本形成外科学会総会
    • Place of Presentation
      横浜
    • Related Report
      2010 Final Research Report 2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi