Pulp regeneration by chemokine
Project/Area Number |
21791872
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Conservative dentistry
|
Research Institution | National Center for Geriatrics and Gerontology |
Principal Investigator |
IOHARA Koichiro 独立行政法人国立長寿医療研究センター, 口腔疾患研究部, 特任研究員 (60435865)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 歯髄再生 / G-CSF / 血管新生 / マイクロアレイ / 歯髄幹細胞 / 遊走因子 / 抜髄 / 感染根管治療 |
Research Abstract |
To examine the angiogenic/proangiogenic properties, gene expression profiles were analyzed by microarray and real-time RT-PCR. The expression of G-CSF was much stronger in pulp CD31-/CD146-SP cells compared with that in adipose, none marrow and artery CD31-/CD146-SP cells. Pulp regeneration after pulpectomy by transplantation of collagen with G-CSF.
|
Report
(4 results)
Research Products
(29 results)