Development of new materials for bone regenerative medicine by applying nano-fiber

• Project/Area Number: 21791954
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Nihon University
• Principal Investigator: TANIMOTO Yasuhiro 日本大学, 松戸歯学部, 准教授 (40312045)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 骨再生材料 / ファイバー / ポリ乳酸 / リン酸カルシウム / ナノファイバー / エレクトロスピニング / 溶液濃度 / アパタイト生成能 / 骨再生医療用材料 / ファイバー添加量 / 気孔率 / 機械的性質 / ポリグリコール酸 / 生分解性 / 組織再生用足場材料

Research Abstract

In this study, a poly(lactic acid)-nano fiber sheet and an alumina mixedβ-tricalcium phosphate were prepared by electro-spinning method and tape-casting method, in order to develop the fiber-based bone regeneration materials. As the result of the characterization, these materials prepared in this study represent the promising materials for use as bone regeneration materials.

Research Products

• [Presentation] Physical properties of sintered tricalcium phosphate laminates with addition of milled Al_2O_3-fibers (2011)
  • Author(s): Yasuhiro Tanimoto、Ryoichiro Uchida、Hideki Teshima、Norihiro Nishiyama、Yo Shibata、Takashi Miyazaki
  • Organizer: 4th International Conference on the Mechanics of Biomaterials and Tissues
  • Place of Presentation: ハワイ・アメリカ
  • Year and Date: 2011-12-11
• [Presentation] Physical properties of sintered tricalcium phosphate laminates with addition of milied Al_2O_3-fibers (2011)
  • Author(s): Yasuhiro Tanimoto, Ryouichiro Uchida, Hideki Teshima, Norihiro Nishiyama, Yo Shibata, Takashi Miyazaki
  • Organizer: 4th International Conference on the Mechanics of Biomaterials and Tissues
  • Place of Presentation: アメリカ・ハワイ
  • Year and Date: 2011-12-11
• [Presentation] Preparation and in vitro behavior of PLA-fiber/HA composite (2010)
  • Author(s): Yasuhiro Tanimoto、Hideki Teshima、Norihiro Nishiyama
  • Organizer: The 88th General Session & Exhibition of the International Association for Dental Research
  • Place of Presentation: バルセロナ・スペイン
  • Year and Date: 2010-07-16
• [Presentation] Preparation and in vitro behavior of PLA-fiber/HA composite (2010)
  • Author(s): Yasuhiro Tanimoto, Hideki Teshima, Norihiro Nishiyama
  • Organizer: The 88th General Session & Exhibition of the International Association for Dental Research
  • Place of Presentation: スペイン・バルセロナ
  • Year and Date: 2010-07-16