Bone augmentation by extention of the periosteum with BMP-2 gene

• Project/Area Number: 21791983
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: University of Yamanashi
• Principal Investigator: ODA Mitsumasa University of Yamanashi, 医学部附属病院, 医員 (90516915)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 口腔外科学一般 / 歯学 / 再生医学

Research Abstract

At heisei 21, we build a experiment methods and selected materials for experiments. Then at heisei 22, we started rabbit bone augmentation by extention of the periosteum with mixed BMP-2 gene and atero-collagen. But we can not get expected bone augmentation. We changed BMP-2 gene to BMP-2 protein, then we can get bone augmentation.