Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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Research Abstract |
We were cultured in Adenoid cystic carcinoma cells. In this study, After the effects of TNFα cytokines on CD44 cleavage were examined in several Adenoid cystic carcinoma cell lines using Western blotting . And we examined relationship between expression of ADAM17 and CD44 cleavage in mechanism for the tumor progression of ACC cell. The treatment of ACC cells with TNFα did not induce the generation of CD44 cleaved. We have to consider that cell lines after stimulation with TNFα, we are looking for localization of CD44 intracellular domain location details.
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