Autograft experiment of the induced bone on the periosteum by absorptive HAp/BMP-2 to mandibular resected region.
| Project/Area Number |
21792027
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Health Sciences University of Hokkaido |
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Principal Investigator |
HINO Jun Health Sciences University of Hokkaido, 歯学部, 助手 (20508709)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 吸収性セラミックス / 生体材料 / 骨膜上骨誘導 / 骨移植 / 移植・再生医療 / 超音波部分溶解析出処理 |
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| Research Abstract |
The supra-periosteal implant, of the biomimctic functionally graded hydroxyapatite (fg-HAp, absorptive HAp)/BMP-2 showed high cell proliferation activity and excellent hard tissue induction. Moreover, it was suggested that the surrounding tissue become a periosteum according to the progress of the bone formation. In addition, the hydroxyapatite modified by a partial dissolution-precipitation technique using supersonic treatment might be improved the ability of hard tissue induction with BMP-2. Because a bony bridge formation between the new bone and the skull was not made, it was thought that the new bone on the periosteum could be removed easily and used for the bone graft.
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Report
(3 results)
Research Products
(7 results)
