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The study of regenerating bone tissue by hematopoietic stem cell from the factor of the alveolar bone grafting

Research Project

Project/Area Number 21792051
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthodontic/Pediatric dentistry
Research InstitutionHokkaido University

Principal Investigator

MATSUNO Mino  北海道大学, 大学院・歯学研究科, 専門研究員 (80374544)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords骨移植 / 歯学 / 口唇裂・口蓋裂 / 骨組織再生 / 造血系幹細胞 / 間葉系幹細胞 / CT
Research Abstract

The alveolar bone grafting is one of the most necessary and important treatments for the achievement of progress satisfactorily othrodontic treatment of the cleft lip and palate patients. The purpose of this study is to examine that the possibility of the regeneration of the alveolar bone tissue by using bone marrow-derived mesenchymal stem cell(BMMSCs) and hematopoietic stem cell(HSCs). As the result, it is considered that the using of both BMMSCs and HSCs is effective method for the bone regeneration.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report

Research Products

(3 results)

All 2012 2011

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] Congenital and Postnatal Factors Inducing Malocclusions in Japanese Unilateral Cleft Lip and Palate Patients-Determination Using Logistic Regression Analysis2012

    • Author(s)
      Takashi S. Kajii, Mohammad Khursheed Alam, Tadashi Mikoya, Akihiko Oyama, Mino Koshikawa-Matsuno, Yuki Sugawara-Kato, Yoshiaki Sato, and Junichiro Iida
    • Journal Title

      The Cleft Palate-Craniofacial Journal

      Volume: (accept)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Presentation] 間葉系幹細胞と造血系幹細胞の併用による骨組織再生の試み2011

    • Author(s)
      松野美乃,菊入崇,佐藤嘉晃,飯田順一郎,鈴木邦明
    • Organizer
      日本矯正歯科学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2011 Final Research Report
  • [Presentation] 間葉系幹細胞と造血系幹細胞の併用による骨組織再生の試み2011

    • Author(s)
      松野美乃
    • Organizer
      第70回日本矯正歯科学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2011 Annual Research Report

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Published: 2009-03-31   Modified: 2016-04-21  

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