• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Role on novel protein in alveolar bone remodeling mechanism of tooth movement

Research Project

Project/Area Number 21792083
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthodontic/Pediatric dentistry
Research InstitutionKyushu University

Principal Investigator

MURAKAMI Ayako  Kyushu University, 歯学研究院, 医員 (10432923)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
KeywordsPRIP / 転写 / スプライシング / 歯牙移動 / 骨リモデリング / 遺伝子発現調節 / 抑制性情報伝逹 / メカニカルストレス
Research Abstract

In this study, we investigated the gene structure of PRIP-2, which exhibited an ubiquitous expression. We found several transcriptional start sites of PRIP-2 gene. This result indicates that PRIP-2 gene produces some transcripts.
To examine the role of PRIP molecule on the alveolar bone remodeling mechanism of tooth movement, we carried out Real-time PCR using tooth movement mice by orthodontic force. There was no significantly difference of the expression level of PRIP-1, PRIP-2 and each subunit of GABAA receptor in brain, between the tooth movement mice and the control.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (2 results)

All 2010 2009

All Presentation (2 results)

  • [Presentation] Studies on characterization of the gene structure and transcriptional regulation of a novel inositol 1,4,5-trisphosphate binding protein, possibly involved in bone metabolism2010

    • Author(s)
      Ayako Murakami, Miho Matsuda, Koushirou Tsutsumi, Masato Hirata, Ichiro Takahashi
    • Organizer
      The 5^<th> International Symposium on Dental and Craniofacial Morphogenesis and Tissue Regeneration : A View from Stem Cell Research
    • Year and Date
      2010-02-05
    • Related Report
      2010 Final Research Report
  • [Presentation] Studies on characterization of the gene structure and transcriptional reglatipn of a novel insitol 1,4,5-trisphosphate binding protein, possibly involved in bone metabolism2009

    • Author(s)
      Ayako Murakami
    • Organizer
      The 5th International Symposium on "Dental and Craniofacial Morphogenesis and Tissue Regeneration : A View from Stem Cell Research
    • Place of Presentation
      Centennial Hall Kyushu University School of Medicine
    • Year and Date
      2009-02-03
    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi