The effects of PRP and LIPUS during tooth movement

Research Project

Project/Area Number	21792097
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Orthodontic/Pediatric dentistry
Research Institution	Showa University
Principal Investigator	SATO Yuki Showa University, 歯学部, 助教 (00384339)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords	歯科医矯正学 / PRP / LIPUS / 歯の移動 / 多血小板血漿 / 破骨細胞
Research Abstract	This study is to clarify the histological effects of PRP administration and LIPUS insonification during tooth movement of rats. PRP component: The number of platelet and white blood cell (monocyte) increased. The tooth movement in 3-day and 7-day PRP+LIPUS groups was significantly faster than other group. Osteoclast numbers of 3-day increased significantly. Proliferation of blood vessels was also found in both PRP group. Destroyed PDL were observed in PRP+LIPUS group. Histologically there is a possibility that PRP or LIPUS induced the metabolic activity in rats, and therefore, led to the promoted tooth movement. However, PRP combined LIPUS may reduced PDL.

Report

(3 results)