Fishing growth rate determinant genes of fish

• Project/Area Number: 21880016
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: General fisheries
• Research Institution: The University of Tokyo
• Principal Investigator: HOSOYA Sho The University of Tokyo, 大学院・農学生命科学研究科, 特任研究員 (60526466)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: トラフグ / 成長速度 / 交雑種 / QTL解析 / BAC

Research Abstract

This study aimed at locating genomic regions which determines species specific body size in fish. We used second generation hybrid (F_2) and backcross (BC) between Takifugu rubripes (fugu) and T. niphobles (kusa-fugu) to conduct QTL analysis for growth rate. In the first year, we locate a QTL harboring 1.5Mbp on a single linkage group of fugu. We introduced a fugu BAC, included the region with highest LOD score, into T. niphobles by microinjection. These injected individuals are to be used to examine the effects of genes included in the BAC.

Research Products

• [Journal Article] Integration of the genetic map and genome assembly of fugu facilitates insights into distinct features of genome evolution in teleosts and mammals. (2011)
  • Author(s): Kai W, Kikuchi K, Tohari S, Chew A, Tay A, Fujiwara A, A Hosoya, Suetake H, Naruse K, Brenner S, Suzuki Y., Venkatesh B.
  • Journal Title: Genome Biol.Evol. (in Press)
  • Peer Reviewed
• [Journal Article] フグ類の多様化をもたらした遺伝子の探索-種間交雑を利用したゲノムワイドマッピング- (2010)
  • Author(s): 菊池潔,甲斐渉,細谷将,末武弘章,鈴木譲
  • Journal Title: 月刊海洋 42巻 Pages: 363-371
• [Presentation] フグのトランスジェネシス (2011)
  • Author(s): 細谷将,穴井康崇,竹内裕,中村修,鈴木重則,水野直樹・田角聡志・鈴木譲・菊池潔
  • Organizer: 日本水産学会春季大会
  • Place of Presentation: 東京
  • Year and Date: 2011-03-28
• [Presentation] フグのトランスジェネシス (2011)
  • Author(s): 細谷将, 穴井康崇, 竹内裕, 中村修, 鈴木重則, 水野直樹・田角聡志・鈴木譲・菊池潔
  • Organizer: 日本水産学会春季大会
  • Place of Presentation: 東京海洋大学(東京)
  • Year and Date: 2011-03-28
• [Presentation] Genetic Basis of Parallel Evolution for the Spiny Scale in the Rapid Radiation of Pufferfishes. (2011)
  • Author(s): Kikuchi K, Kai W, Kuroyanagi M, Nozawa A, Hosoy, S, Suetake H, Suzuki Y
  • Organizer: The 20th CDB Meeting Molecular Bases for Evolution of Complex Traits
  • Place of Presentation: Hyougo
  • Year and Date: 2011-02-23
• [Presentation] フグにおける形態多様化の遺伝的背景:種間交配を利用したゲノムワイド連鎖解析 (2010)
  • Author(s): 甲斐渉,細谷将,菊池潔,黒柳美和,合田知樹,野澤碧,末武弘章,鈴木譲
  • Organizer: 日本進化学会第12回東京大会
  • Place of Presentation: 東京
  • Year and Date: 2010-08-05
• [Presentation] Genetic architecture of interspecific differences in growth of pufferfishes. (2010)
  • Author(s): Hosoya S, Kikuchi K, Kai W, Mizuno N, Suetake H, Suzuki Y
  • Organizer: 9th International Congress for the Biology of Fish.
  • Place of Presentation: Spain, Barcelona.
  • Year and Date: 2010-07-05
• [Presentation] Genetic architecture of interspecific differences in growth of pufferfishes (2010)
  • Author(s): Hosoya, S, Kikuchi, K, Kai, W, Mizuno, N, Suetake, H, Suzuki, Y
  • Organizer: 9th International Congress for the Biology of Fish
  • Place of Presentation: Spain, Barcelona
  • Year and Date: 2010-07-05
• [Presentation] フグの脊椎骨数と成長を支配する遺伝子の関係 (2010)
  • Author(s): 合田知樹,細谷将,甲斐渉,菊池潔,水野直樹,末武弘章,石川智士,鯉江洋,鈴木譲
  • Organizer: 平成22年日本水産学会春季大会
  • Place of Presentation: 神奈川
  • Year and Date: 2010-03-27
• [Presentation] フグ類の多様化をもたらした遺伝子の探索:種間交雑を利用したゲノムワイドQTL解析 (2009)
  • Author(s): 菊池潔,甲斐渉,細谷将,木戸慎一,末武弘章,鈴木譲
  • Organizer: 2009年度日本魚類学会シンポジウム
  • Place of Presentation: 東京(招待講演)
  • Year and Date: 2009-10-12
• [Remarks] ホームページ等