Study of craniofacial tissue induction by aggregation culture
| Project/Area Number |
21890161
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
NABESHIMA Koh Hiroshima University, 病院, 歯科診療医 (10550999)
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| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000)
Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
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| Keywords | アニマルキャップ / ES細胞 / 再生医療 / 顔面組織 / 顎顔面組織 |
|---|
| Research Abstract |
By the Xenopus aggregation method, aggregate inducing cartilage tissues of maxillofacial region, which activin A-treated cells were mixed with untreated cells at a ratio of 1:5, and aggregate inducing notochord at a ratio of 1:1 were generated. when 1:5 and 1:1 aggregate were subjected to a microarray experiment using Xenopus DNA microarray chips representing over 8,000 unigenes, we identified 51 genes that are specifically up regulated in 1:5 aggregate. Of the 51, 9 genes have been linked to neural crest induction. Among them, we investigated any genes that haven't been involved in neural crest and revealed that syntenin and tamalin genes expressed in maxillofacial region of Xenopus.
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Report
(3 results)
Research Products
(5 results)
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[Presentation] 当科で治療した舌癌の臨床的検討2009
Author(s)
岡本康正, 伊藤翼, 山崎佐知子, 岡崎文彦, 藤井良典, 鍋島巧, 竹末奈七子, 木村直大, 石田康隆, 浜名智昭, 福井康人, 角健作, 神田拓, 新谷智章, 小泉浩一, 吉岡幸男, 谷亮冶, 林堂安貴, 虎谷茂昭, 小林雅史, 原潤一, 有田裕一, 坂本哲彦, 越智康, 谷本裕, 佐渡友浩, 芳村善道, 村上光寿, 間島徹, 阪本知二, 岡本哲治
Organizer
第57回NPO法人日本口腔科学会中国・四国地方部会
Place of Presentation
岡山県倉敷市
Year and Date
2009-11-14
Related Report
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[Presentation] 表在性口腔癌に対する光線力学療法(PDT)2009
Author(s)
虎谷茂昭, 谷亮治, 藤井良典, 松本真司, 鍋島巧, 竹末奈七子, 木村直大, 石田康隆, 福井康人, 北村直也, 岡本康正, 新谷智章, 小泉浩一, 小林雅史, 吉岡幸男, 岡本哲治
Organizer
第63回特定非営利活動法人日本口腔科学会学術集会
Place of Presentation
浜松市
Year and Date
2009-04-17
Related Report
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