gap junction contributes to neuropathic pain following mental nerve injury

• Project/Area Number: 21890162
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: Hiroshima University
• Principal Investigator: TAKAHASHI Kouji Hiroshima University, 病院, 歯科診療医 (30551048)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2010: ¥1,235,000 (Direct Cost: ¥950,000、Indirect Cost: ¥285,000); Fiscal Year 2009: ¥1,365,000 (Direct Cost: ¥1,050,000、Indirect Cost: ¥315,000)
• Keywords: 解剖学 / 慢性疼痛 / 星状膠細胞 / 小膠細胞

Research Abstract

These results suggest that IL-1beta in the Vc plays an important role in the development of extra-territorial tactile allodynia/hyperalgesia after MN transection.

Research Products

• [Journal Article] IL-1beta in the trigeminal subnucleus caudalis contributes to extra-territorial allodynia/hyperalgesia following a trigeminal nerve injury, European Journal of Pain (2010)
  • Author(s): Kouji Takahashi
  • Journal Title: 電子媒体
• [Journal Article] IL-1beta in the trigeminal subnucleus caudalis contributes to extra-territorial allodynia/hyperalgesia following a trigeminal nerve injury (2010)
  • Author(s): Kouji Takahashi
  • Journal Title: European Journal of Pain Volume: (電子媒体)
  • Peer Reviewed
• [Presentation] Astrocytic Interleukin-1beta contributes to neuropathic pain following mental nerve injury (2010)
  • Author(s): Kouji Takahashi
  • Organizer: LADR
  • Place of Presentation: Barcelona, Spain
• [Presentation] Astrocytic Interleukin-1beta contributes to neuropathic pain following mental nerve injury (2010)
  • Author(s): Kouji Takahashi
  • Organizer: IADR
  • Place of Presentation: Barcelona, Spain