| Project/Area Number |
21890286
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Biological pharmacy
|
|---|
| Research Institution | Kobe Pharmaceutical University |
|---|
Principal Investigator |
MIYATA Shinji Kobe Pharmaceutical University, 薬学部, 特別契約研究員 (60533792)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥2,652,000 (Direct Cost: ¥2,040,000、Indirect Cost: ¥612,000)
Fiscal Year 2010: ¥1,261,000 (Direct Cost: ¥970,000、Indirect Cost: ¥291,000)
Fiscal Year 2009: ¥1,391,000 (Direct Cost: ¥1,070,000、Indirect Cost: ¥321,000)
|
|---|
| Keywords | コンドロイチン硫酸プロテオグリカン / コンドロイチン硫酸 / プロテオグリカン / 神経可塑性 / 神経再生 / 抑制性神経細胞 / 臨界期可塑性 / 糖鎖生物学 |
|---|
| Research Abstract |
Cortical plasticity is most evident during a critical period in early life, but the mechanisms that restrict plasticity after the critical period are poorly understood. In this study I show that a structural changes of chondroitin sulfate proteoglycans, components of the brain extracellular matrix, leads to the termination of the critical period.
|
