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Generation mechanisms of affect and decision-making based on predictive processing of interoception

Research Project

Project/Area Number 21H04420
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Review Section Medium-sized Section 10:Psychology and related fields
Research InstitutionNagoya University

Principal Investigator

Ohira Hideki  名古屋大学, 情報学研究科, 教授 (90221837)

Co-Investigator(Kenkyū-buntansha) 上野 大介  京都府立医科大学, 医学(系)研究科(研究院), 客員講師 (00760589)
遠山 朝子  一橋大学, 社会科学高等研究院, 講師 (10816549)
田邊 宏樹  名古屋大学, 情報学研究科, 教授 (20414021)
木村 健太  国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 研究グループ長 (40589272)
片平 健太郎  国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 主任研究員 (60569218)
齋藤 菜月  名古屋大学, 情報学研究科, 研究員 (60844834)
日永田 智絵  奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 (70807388)
長井 隆行  大阪大学, 大学院基礎工学研究科, 教授 (40303010)
Project Period (FY) 2021-04-05 – 2025-03-31
Project Status Completed (Fiscal Year 2024)
Budget Amount *help
¥41,860,000 (Direct Cost: ¥32,200,000、Indirect Cost: ¥9,660,000)
Fiscal Year 2024: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2023: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2022: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2021: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Keywords生理 / 予測 / 内受容感覚 / 感情 / 意思決定 / 脳 / 身体 / 計算論モデル
Outline of Research at the Start

身体内部信号の予測的処理から生じる内受容感覚が、感情を創発し意思決定を導く、という仮説を次のように検証する。1)内受容感覚の予測的処理に基づく身体状態の制御、感情の創発、意思決定の過程を表現する計算論モデルを構築する。2)内受容感覚を操作して意思決定課題を施行し、そこで得られる行動、脳活動、身体活動のデータを計算論モデルにより解析し仮説を検証する。3)人間の身体と計測装置を融合したシステムであるセンサロイドを製作し、そこで得られたデータのモデル化により、感情概念が生成され主観的な情動が経験される原理を探求する。4)身体症状症を内受容感覚の不全と捉え、その特性を計算論モデルと実験により検討する。

Outline of Final Research Achievements

Studies measuring brain activity and physiological responses during decision-making tasks revealed the involvement of the striatum which is related to reward prediction error and its absolute value calculation, as well as the insular cortex, which is closely associated with interoception. These findings suggest that the predictive processing of interoception plays a crucial role in the mechanisms of decision-making. In healthy individuals, training that provided feedback on performance in a heartbeat detection task improved the interoceptive accuracy, but this was difficult for patients with somatic symptom disorder. It was suggested that weakened functional connectivity between the insular cortex and other brain regions is a contributing factor for weakened interoception in patients. A model in which emotional concepts are generated and subjective emotions are experienced was proposed based on data obtained from a sensoroid that integrates the human body with measurement devices.

Academic Significance and Societal Importance of the Research Achievements

本研究の研究期間の間に内受容感覚への研究関心が顕著に高まり、内受容感覚が予測的処理に基づいて作動し、それが感情の源泉となること、その不調が心身の疾患のリスク要因となることについて、多くの研究者が合意するに至った。しかしそのメカニズムの多くは以前として仮説の段階にあり、実証的な検証が進んでいない。本研究は、健常者を対象にした脳と身体の機能の検証、身体症状症患者を対象にした臨床研究、さらに計算論モデルによる検討により、この問題に統合的にアプローチし、多くの有益な知見を得た。またその知見は学術的のみならず、臨床応用や健常者のウエルビーイングを高めるための応用など、実社会にもインパクトを与える得る。

Report

(6 results)
  • 2024 Annual Research Report   Final Research Report ( PDF )
  • 2023 Annual Research Report
  • 2022 Annual Research Report
  • 2021 Comments on the Screening Results   Annual Research Report
  • Research Products

    (47 results)

All 2025 2024 2023 2022 2021 Other

All Int'l Joint Research (2 results) Journal Article (26 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 25 results,  Open Access: 25 results) Presentation (15 results) (of which Int'l Joint Research: 5 results,  Invited: 12 results) Book (4 results)

  • [Int'l Joint Research] University of Sussex(英国)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] Northeastern University(米国)

    • Related Report
      2023 Annual Research Report
  • [Journal Article] Women with premenstrual syndrome exhibit high interoceptive accuracy, but low awareness, with parasympathetic rebound responses from stress2025

    • Author(s)
      YC Suzuki, H Ohira
    • Journal Title

      Frontiers in Neuroscience

      Volume: 19 Pages: 1489225-1489225

    • DOI

      10.3389/fnins.2025.1489225

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The association between interoception and olfactory affective responses2024

    • Author(s)
      T Arai, T Komano, T Munakata, H Ohira
    • Journal Title

      Biological Psychology

      Volume: 193 Pages: 108878-108878

    • DOI

      10.1016/j.biopsycho.2024.108878

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The influence of cardiac synchronisation on self-attribution to external objects in male participants2024

    • Author(s)
      Shibata Hiroshi、Harada Tokiko、Ohira Hideki
    • Journal Title

      Frontiers in Psychology

      Volume: 15 Pages: 1442942-1442942

    • DOI

      10.3389/fpsyg.2024.1442942

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Somatic symptoms and Its association with anxiety and interoception2024

    • Author(s)
      VVR Maulina, H Ohira
    • Journal Title

      ANIMA Indonesian Psychological Journal

      Volume: 39 Issue: 2 Pages: E04-E04

    • DOI

      10.24123/aipj.v39i2.6327

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Striatal GABA levels correlate with risk sensitivity in monetary loss2024

    • Author(s)
      Kondo Hirohito M.、Oba Takeyuki、Ezaki Takahiro、Kochiyama Takanori、Shimada Yasuhiro、Ohira Hideki
    • Journal Title

      Frontiers in Neuroscience

      Volume: 18 Pages: 1439656-1439656

    • DOI

      10.3389/fnins.2024.1439656

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of brain-autonomic activities and task accuracy under cognitive load: a pilot study using electroencephalogram, autonomic activity measurements, and arousal level estimated by machine learning2024

    • Author(s)
      Sazuka Naoya、Katsumata Koki、Komoriya Yota、Oba Takeyuki、Ohira Hideki
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 18 Pages: 1272121-1272121

    • DOI

      10.3389/fnhum.2024.1272121

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Endogenous melatonin and impulsivity in humans2024

    • Author(s)
      M Kurihara, H Ohira
    • Journal Title

      Neuroendocrinology Letters

      Volume: 45 Pages: 1-6

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between salivary melatonin and interoceptive awareness2024

    • Author(s)
      M Kurihara, H Ohira
    • Journal Title

      Neuroendocrinology Letters

      Volume: 45 Pages: 1-5

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The autonomic nervous system and decision-making2023

    • Author(s)
      大平 英樹
    • Journal Title

      The Autonomic Nervous System

      Volume: 60 Issue: 4 Pages: 144-150

    • DOI

      10.32272/ans.60.4_144

    • ISSN
      0288-9250, 2434-7035
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] PREDICTIVE PROCESSING AND EMERGENCE OF THE HUMAN MIND2023

    • Author(s)
      Ohira Hideki
    • Journal Title

      PSYCHOLOGIA

      Volume: 65 Issue: 2 Pages: 134-159

    • DOI

      10.2117/psysoc.2023-B032

    • ISSN
      0033-2852, 1347-5916
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Integration of interoception, decision-making, and affect: Allostasis as predictive processing2023

    • Author(s)
      Ohira, H.
    • Journal Title

      Brain and Nerve

      Volume: 75 Pages: 1197-1203

    • Related Report
      2023 Annual Research Report
  • [Journal Article] Editorial: Interoception and the autonomic nervous system: Investigating affect, decision-making, and mental health2023

    • Author(s)
      Ueno Daisuke、Ohira Hideki、Narumoto Jin
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 1-2

    • DOI

      10.3389/fnins.2022.1130324

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of interoceptive accuracy on timing control in the synchronization tapping task2023

    • Author(s)
      Tomyta Kenta、Katahira Kentaro、Ohira Hideki
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 01-09

    • DOI

      10.3389/fnins.2022.907836

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cardiac cycle affects risky decision-making2023

    • Author(s)
      Kimura Kenta、Kanayama Noriaki、Katahira Kentaro
    • Journal Title

      Biological Psychology

      Volume: 176 Pages: 108471-108471

    • DOI

      10.1016/j.biopsycho.2022.108471

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mothers’ interoceptive sensibility mediates affective interaction between mother and infant2022

    • Author(s)
      Suga Ayami、Naruto Yosuke、Maulina Venie Viktoria Rondang、Uraguchi Maki、Ozaki Yuka、Ohira Hideki
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 1-14

    • DOI

      10.1038/s41598-022-09988-y

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Interoceptive Accuracy Did Not Affect Moral Decision-Making, but Affect Regret Rating for One’s Moral Choices2022

    • Author(s)
      Tamura Kaho、Kobayashi Yoshinari、Ohira Hideki
    • Journal Title

      Frontiers in Psychology

      Volume: 12 Pages: 1-9

    • DOI

      10.3389/fpsyg.2021.746897

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Interoceptive accuracy correlates with precision of time perception in the millisecond range2022

    • Author(s)
      Uraguchi Maki、Maulina Venie Viktoria Rondang、Ohira Hideki
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 1-16

    • DOI

      10.3389/fnins.2022.993491

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Somatic Symptoms: Association Among Affective State, Subjective Body Perception, and Spiritual Belief in Japan and Indonesia2022

    • Author(s)
      Maulina Venie Viktoria Rondang、Yogo Masao、Ohira Hideki
    • Journal Title

      Frontiers in Psychology

      Volume: 13 Pages: 851888-851888

    • DOI

      10.3389/fpsyg.2022.851888

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Influences of Reinforcement and Choice Histories on Choice Behavior in Actor-Critic Learning2022

    • Author(s)
      Katahira Kentaro、Kimura Kenta
    • Journal Title

      Computational Brain & Behavior

      Volume: 1 Issue: 2 Pages: 1-23

    • DOI

      10.1007/s42113-022-00145-2

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cardiac Cycle Affects the Asymmetric Value Updating in Instrumental Reward Learning2022

    • Author(s)
      Kimura Kenta、Kanayama Noriaki、Toyama Asako、Katahira Kentaro
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 1-10

    • DOI

      10.3389/fnins.2022.889440

    • Related Report
      2022 Annual Research Report 2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Survey and perspective on social emotions in robotics2022

    • Author(s)
      Hieida Chie、Nagai Takayuki
    • Journal Title

      Advanced Robotics

      Volume: 36 Issue: 1-2 Pages: 17-32

    • DOI

      10.1080/01691864.2021.2012512

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Psychosocial characteristics of victims of special fraud among Japanese older adults: A cross-sectional study using scam vulnerability scale2022

    • Author(s)
      Ueno Daisuke、Arakawa Masashi、Fujii Yasunori、Amano Shoka、Kato Yuka、Matsuoka Teruyuki、Narumoto Jin
    • Journal Title

      Frontiers in Psychology

      Volume: 13

    • DOI

      10.3389/fpsyg.2022.960442

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Brain Neural Underpinnings of Interoception and Decision-Making in Alzheimer's Disease: A Narrative Review2022

    • Author(s)
      Sun Weiyi、Ueno Daisuke、Narumoto Jin
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 946136-946136

    • DOI

      10.3389/fnins.2022.946136

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A learning mechanism shaping risk preferences and a preliminary test of its relationship with psychopathic traits2021

    • Author(s)
      Oba Takeyuki, Katahira Kentaro, Ohira Hideki
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 20853-20853

    • DOI

      10.1038/s41598-021-00358-8

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Revisiting the importance of model fitting for model-based fMRI: It does matter in computational psychiatry2021

    • Author(s)
      Katahira Kentaro, Toyama Asako
    • Journal Title

      PLOS Computational Biology

      Volume: 17 Issue: 2 Pages: e1008738-e1008738

    • DOI

      10.1371/journal.pcbi.1008738

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Editorial: Language and Robotics2021

    • Author(s)
      Taniguchi Tadahiro、Horii Takato、Hinaut Xavier、Spranger Michael、Mochihashi Daichi、Nagai Takayuki
    • Journal Title

      Frontiers in Robotics and AI

      Volume: 8

    • DOI

      10.3389/frobt.2021.674832

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Integration of interoception, decision-making, and emotion: predictive processing of allostasis2024

    • Author(s)
      Ohira, H.
    • Organizer
      The Annual Meeting of Physiological Society of Japan
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] Predictive processing of interoception as a base of mentality:Implications for morality2023

    • Author(s)
      Hideki Ohira
    • Organizer
      1st International Meeting on Robo-Ethics and Philosophy between Italy and Japan
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A study for the exploration and exploitation strategy of human based on restless two-armed bandit task2022

    • Author(s)
      J Tian, C Hieida, J Yoshimoto, K Kimura, H Ohira, K Ikeda
    • Organizer
      情報処理学会第 84 回全国大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Emergence of emotion and decision-making based on predictive processing of interoception: Implications for emotional intelligence2022

    • Author(s)
      Hideki Ohira
    • Organizer
      International Conference on Emotional Intelligence 2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 内受容感覚と意思決定の関連とそれに伴うフィーリング2022

    • Author(s)
      大平英樹
    • Organizer
      生理学研究所研究会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 自律神経と意思決定2022

    • Author(s)
      大平英樹
    • Organizer
      第75回日本自律神経学会総会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] Affective decision-making based on interoceptive predictive processing: Implications for clinical issues2022

    • Author(s)
      Hideki Ohira
    • Organizer
      NTTR Webinar (online)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 内受容感覚の予測的処理に基づく感情と意思決定の創発ー遺伝要因と環境要因の寄与ー2022

    • Author(s)
      大平英樹
    • Organizer
      日本双生児研究学会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 生物学から宗教まで-統合的視点を求めて-2021

    • Author(s)
      大平英樹
    • Organizer
      日本感情心理学会第29回大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 現象と概念の統合2021

    • Author(s)
      大平英樹
    • Organizer
      日本心理学会第85回大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 痛みのモデルーベイズ脳仮説からの視点ー2021

    • Author(s)
      大平英樹
    • Organizer
      日本心理学会第85回大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 感情史・心理学・神経科学2021

    • Author(s)
      大平英樹
    • Organizer
      書評シンポジウム ヤン・プランパー『感情史の始まり』
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 内受容感覚の予測的処理とそのモデリング2021

    • Author(s)
      大平英樹
    • Organizer
      感情のかけ橋シンポジウム2022
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Slow EEG fluctuation and heart rate variability reflects flexible adjustment to cognitive load2021

    • Author(s)
      Naoya Sazuka, Koki Katsumata, Yota Komoriya, Takeyuki Oba, Hideki Ohira
    • Organizer
      EMBC Conference 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Slow EEG fluctuation reflects cognitive load and affective arousal2021

    • Author(s)
      Naoya Sazuka, Koki Katsumata, Yota Komoriya, Takeyuki Oba, Hideki Ohir
    • Organizer
      Annual Conference of Society for Affective Science
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Book] 感情心理学・入門 改訂版2024

    • Author(s)
      大平英樹(編著)
    • Total Pages
      296
    • Publisher
      有斐閣
    • ISBN
      464122238X
    • Related Report
      2024 Annual Research Report
  • [Book] 認知科学講座4 心をとらえるフレームワークの展開2022

    • Author(s)
      横澤一彦(編) 大平英樹が1章を執筆
    • Total Pages
      272
    • Publisher
      東京大学出版会
    • ISBN
      9784130152044
    • Related Report
      2022 Annual Research Report
  • [Book] 予測と創発2022

    • Author(s)
      中村靖子(編) 大平英樹が1章を執筆
    • Total Pages
      450
    • Publisher
      春風社
    • ISBN
      4861108365
    • Related Report
      2022 Annual Research Report
  • [Book] 我感ずる、ゆえに我あり2022

    • Author(s)
      A・D・(バド) クレイグ、花本 知子(訳)、大平 英樹(監修)
    • Total Pages
      756
    • Publisher
      青灯社
    • ISBN
      4862281222
    • Related Report
      2022 Annual Research Report

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Published: 2021-04-28   Modified: 2026-01-16  

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