Elucidating the role of cancer stem cells in the metastatic progression of pancreatic neuroendocrine tumors

• Project/Area Number: 21K15498
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 50010:Tumor biology-related
• Research Institution: National Cancer Center Japan
• Principal Investigator: カポダッノ イレニア 国立研究開発法人国立がん研究センター, 研究所, 特任研究員 (60889187)
• Project Period (FY): 2021-04-01 – 2023-03-31
• Project Status: Granted (Fiscal Year 2021)
• Budget Amount: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000); Fiscal Year 2022: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2021: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: cancer stem cells / PNETs / diagnostic markers / metastases

Outline of Research at the Start

Pancreatic neuroendocrine tumors are rare tumors that arise from hormone-producing cells in the pancreas. For these tumors, no curative treatment is currently available. The aim of this study is to identify novel drug targets for improving the outcome of patients diagnosed with this rare disease.