Elucidation of regulation mechanism of calcification in marine organisms toward preservation of global environment
| Project/Area Number |
22228006
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| Research Category |
Grant-in-Aid for Scientific Research (S)
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| Allocation Type | Single-year Grants |
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| Research Field |
Boundary agriculture
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOGURE Toshihiro 東京大学, 大学院・理学系研究科, 准教授 (50282728)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥152,750,000 (Direct Cost: ¥117,500,000、Indirect Cost: ¥35,250,000)
Fiscal Year 2012: ¥48,360,000 (Direct Cost: ¥37,200,000、Indirect Cost: ¥11,160,000)
Fiscal Year 2011: ¥46,930,000 (Direct Cost: ¥36,100,000、Indirect Cost: ¥10,830,000)
Fiscal Year 2010: ¥57,460,000 (Direct Cost: ¥44,200,000、Indirect Cost: ¥13,260,000)
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| Keywords | 海洋生物 / 石灰化 / 地球環境保全 / 電子顕微鏡観察 / 二酸化炭素 / 有機基質 / 有機無機相互作用 / 結晶多形 / 基質タンパク質 / バイオミネラリゼーション / その場観察 / 温室効果ガス / サンゴ / 軟体動物 |
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| Research Abstract |
We tried to clarify the mechanism of calcification by characterizing organic compounds extracted and purified from calcified tissues of some representative marine organisms including corals and coccolithophores. As a result, more than 10 novel proteins and some known compounds related to calcification were identified. On the basis of the results of functional analyses and microscopic observation, we proposed a common model for calcification in terms of distribution and function of organic matrices.
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| Assessment Rating |
Verification Result (Rating)
A
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Report
(5 results)
Research Products
(152 results)
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[Presentation] GSP-37, a novel goldfish scale matrix protein:identification, localization and functional analysis2012
Author(s)
K.Miyabe, D.Tokunaga, H. Endo, H.Inoue, M. Suzuki, N. Tsutsui, N.Yokoo, T. Kogure and Hiromichi Nagasawa
Place of Presentation
Metropolitan University, Leads, UK
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