|Budget Amount *help
¥45,630,000 (Direct Cost: ¥35,100,000、Indirect Cost: ¥10,530,000)
Fiscal Year 2013: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Fiscal Year 2012: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Fiscal Year 2011: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Fiscal Year 2010: ¥12,480,000 (Direct Cost: ¥9,600,000、Indirect Cost: ¥2,880,000)
The purpose of this study is to clarify the mystery of AIDS pandemic (when, where and how did it occur?) as well as the origin of HIV. To do so, we have expedited into far remote provinces in both Democratic Republic of Congo and Republic of Congo. In addition to the conventional molecular epidemiological techniquues, we also employed the so-called second generation high-throughput DNA sequencer. So far the areas showing the most diversified profiles of HIV genotypes are the central region of Congo basin and nearby areas the majority of which is covered with the giant Congo River and its numerous branch rivers. In those areas, not only a great variety of genotypes of HIV strains are co-circulating but also new types of viruses seem to be continuously generated with high probability by way of dual infection of two different genotypic HIV strains and recombination of their genomes as a natural consequent event.