In situ visualization of wound healing using collagen-sensitive optical microscopy
| Project/Area Number |
22300154
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | The University of Tokushima |
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Principal Investigator |
YASUI Takeshi 徳島大学, 大学院・ソシオテクノサイエンス研究部, 教授 (70314408)
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| Co-Investigator(Kenkyū-buntansha) |
ARAKI Tsutomu 大阪大学, 大学院・基礎工学研究科, 教授 (50136214)
FUKUSHIMA Shu-ichiro 大阪大学, 大学院・基礎工学研究科, 助教 (40362644)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2012: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2011: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Keywords | 応用光学 / 量子光工学 / 細胞・組織 / コラーゲン / 創傷治癒 / 非線形光学顕微鏡 / 応用光学・量子光工学 |
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| Research Abstract |
We performed time series monitoring of burned dermal collagen fiber using collagen-sensitive second-harmonic-generation (SHG) microscopy. SHG images of dermal collagen fiber significantly varied depending on the degree of the skin burn, indicating a potential for an optical burn assessment. Furthermore, we successfully observed the dynamics of wound healing process from the viewpoint of collagen.
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Report
(4 results)
Research Products
(52 results)
