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Development of New technology to Capture Circulating Tumor Cells Using an AC Electric Field

Research Project

Project/Area Number 22390264
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionAkita University

Principal Investigator

OGAWA Jun-ichi  秋田大学, 大学院・医学系研究科, 教授 (20112774)

Co-Investigator(Kenkyū-buntansha) MINAMIYA Yoshihiro  秋田大学, 大学院・医学系研究科, 准教授 (30239321)
Research Collaborator AKAGAMI Yo-ichi  秋田県産業技術センター, 部長
NAKAMURA Ryuta  秋田県産業技術センター, 研究員
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2012: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2011: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2010: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Keywords肺癌 / 血中癌細胞 / EpCAM / 電界 / 血中浮遊がん細胞 / 抗原抗体反応 / 磁性ビーズ / 癌 / 血中浮遊癌細胞
Research Abstract

Cancer cell capture in the blood has been studied in many ways. However, the purity of the cancer cells to be obtained is low and could not be applied in the decision of treatment and diagnosis. This study aimed to develop technologies to get the cancer cells with high purity from the blood. We investigated the recovery rate of cancer cells using an electric field non-contact stirring technique we have developed. However, it was not very good results. This technique was not able to stir the small amount of liquid uniformly. To solve this, we developed a water repellent ring to uniform the stirring. Stirring has become uniform using this ring. Study period was ended, but is continued further studied using this.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (1 results)

All 2011

All Journal Article (1 results)

  • [Journal Article] A novel immunohistochemical staining method allows ultrarapid detection of lymph node micrometastases while conserving antibody2011

    • Author(s)
      Toda H, Minamiya Y, Kagaya M, Nanjo H, Akagami Y, Saito H, Ito M, Konno H, Motoyama S, Ogawa J.
    • Journal Title

      Acta Histochem Cytochem

      Volume: 29;44 Pages: 133-9

    • NAID

      130000722777

    • Related Report
      2012 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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