Hair Regeneration using cultured human fibroblasts and keratynocytes

• Project/Area Number: 22390332
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Plastic surgery
• Research Institution: Keio University
• Principal Investigator: KISHI Kazuo 慶應義塾大学, 医学部, 教授 (40224919)
• Co-Investigator(Kenkyū-buntansha): SAKAMOTO Yoshiaki 慶應義塾大学, 医学部, 助教 (10464835) ; KUBOTA Yoshiaki 慶應義塾大学, 医学部, 特任講師 (50348687) ; 岡部 圭介 慶應義塾大学, 医学部, 研究員 (50445350)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000); Fiscal Year 2012: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000); Fiscal Year 2011: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000); Fiscal Year 2010: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
• Keywords: 再生医学 / 毛包 / 再生医療 / 再生 / 皮膚

Research Abstract

The purpose of the present study is to regenerate complete skin including hair follicles and appendages using human fibroblasts and keratinocytes based on our previous study using mice. Also, the proper condition of cultivation for regeneration was determ

Research Products

• [Journal Article] Fetal skin possesses the ability toregenerate completely: complete regeneration of skin (2012)
  • Author(s): Kishi K, Okabe K, Shimizu R, Kubota Y.
  • Journal Title: Keio J Med. Volume: 61(4) Pages: 101-8
  • Peer Reviewed
• [Journal Article] Skin graft (2012)
  • Author(s): Shimizu R, Kishi K.
  • Journal Title: Plast Surg Int. Volume: 2012 Pages: 563493-563493
  • DOI: 10.1155/2012/563493
  • Peer Reviewed
• [Journal Article] Fetal skin possess an ability to regenerate completely (2012)
  • Author(s): Kishi K
  • Journal Title: Keio Journal of Medicine Volume: 61 Pages: 101-108
  • Peer Reviewed
• [Journal Article] Sphere formation restores and confers hair-inducing capacity in cultured mesenchymal cells (2011)
  • Author(s): Shimizu R et al.(Kishi K ; 6人中6番)
  • Journal Title: Exp Dermatol Volume: 20 Issue: 8 Pages: 679-81
  • DOI: 10.1111/j.1600-0625.2011.01281.x
  • Peer Reviewed
• [Presentation] 線維芽細胞凝集塊形成による非対称性脱分化 (2011)
  • Author(s): 清水瑠加, 他
  • Organizer: 第20回日本形成外科学会基礎学術集会
  • Place of Presentation: ハイアットリージェンシー(東京)
  • Year and Date: 2011-10-06