Bone regeneration following vascular network formation

• Project/Area Number: 22390384
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Nagoya University
• Principal Investigator: HIBI Hideharu 名古屋大学, 医学系研究科, 准教授 (90345885)
• Co-Investigator(Kenkyū-buntansha): UEDA Minoru 名古屋大学, 大学院・医学系研究科, 教授 (00151803)
• Co-Investigator(Renkei-kenkyūsha): YAMAMOTO Akihito 名古屋大学, 大学院・医学系研究科, 准教授 (50244083) ; KATAGIRI Wataru 名古屋大学, 医学部附属病院, 助教 (10437030)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000); Fiscal Year 2012: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2010: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
• Keywords: 再生医学 / 細胞・組織 / 歯学 / 再生医療 / 組織再生 / 骨再生 / 骨延長 / SDF-1

Research Abstract

A group of cytokines effective in angiogenesis were found through analysis of distraction osteogenesis. Effective bone regeneration following vascular network formation has been shown in vivoa n d in vitroanalysis. It is important to prepare vascular network in bone defect region for bone regeneration therapy.

Research Products

• [Journal Article] Novel appplication oof stem cell-derived faactors for pperiodontal regeneratioon (2013)
  • Author(s): Innukai T, Katagiri W, Yosshimi R, Osuugi M, Kawai T, HHibi H, Uedaa M
  • Journal Title: Biiochemical aand Biophysical Researrch Coommunicationns Volume: 430(2) Pages: 7763-768
  • Peer Reviewed
• [Journal Article] Novel application of stem cell-derived factors for periodontal regeneration (2013)
  • Author(s): Inukai T
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 430 Issue: 2 Pages: 763-768
  • DOI: 10.1016/j.bbrc.2012.11.074
  • Peer Reviewed
• [Journal Article] Human dental pulpp-derived sttem ceells promotee locomotor rrecovery aftter coomplete trannsection of the rat spinnal coord by multiiple neuro-rregenerativve meechanisms (2012)
  • Author(s): Saakai K, Yamaamoto A, Mattsubara K,Naakamura S, NNaruse M, Yaamagata M,Saakamoto K, TTauchi R, Wakkao N, ImagaamaS, Hibi H, Kaadomatsu K, Ishiguro NN,Ueeda M
  • Journal Title: Journal of Cclinical Innvestigation Volume: 122(1) Pages: 800-90
  • Peer Reviewed
• [Journal Article] Conditioned meddia frrom mesenchyymal stem ceells enhancced boone regeneraation in ratt calvarial boone defects. (2012)
  • Author(s): Ossugi M, Katagiri W, Yoshhimi R, Inukkai T, Hibi H, Ueeda M
  • Journal Title: Tissue Enggineering Paart A Volume: 18(13-14) Pages: 1479-1489
  • Peer Reviewed
• [Journal Article] Interfacees of titaniium implants and a vascularized osteocutaneouus scapular graft revissed with distracttion osteogeenesis. (2012)
  • Author(s): Hiibi H, Ueda M
  • Journal Title: Journal of Craniofaciall Surgery Volume: 233(5) Pages: 1549-1550
  • Peer Reviewed
• [Journal Article] Mesenchymal stromal ceells of human umbilical cord Whartonn's jelly accelerate wound healiing by paracrine mechanisms. (2012)
  • Author(s): Shohara R, Yamamoto A, Takikawa S Iwase A, Hibi H, Kikkawa F, Ueda M
  • Journal Title: Cytotherappy Volume: 14(10) Pages: 1171-1181
  • Peer Reviewed
• [Journal Article] Conditioned media from mesenchymal stem cells enhanced bone regeneration in rat calvarial bone defects (2012)
  • Author(s): Osugi M.
  • Journal Title: Tissue Engineering Part A Volume: 18 Issue: 13-14 Pages: 1479-1489
  • DOI: 10.1089/ten.tea.2011.0325
  • Peer Reviewed
• [Journal Article] Interfaces of titanium implants and a vascularized osteocutaneous scapular graft revised with distraction osteogenesis (2012)
  • Author(s): Hibi H
  • Journal Title: Journal of Craniofacial Surgery Volume: 23 Issue: 5 Pages: 1549-1550
  • DOI: 10.1097/scs.0b013e3182587db2
  • Peer Reviewed
• [Journal Article] Mesenchymal stromal cells of human umbilical cord Wharton’s jelly accelerate wound healing by paracrine mechanisms (2012)
  • Author(s): Shohara R
  • Journal Title: Cytotherapy Volume: 14 Issue: 10 Pages: 1171-1181
  • DOI: 10.3109/14653249.2012.706705
  • Peer Reviewed
• [Journal Article] Multifaceted neuro-regenerative activities of human dental pulp stem cells promote locomotor recovery after complete transection of the rat spinal cord (2012)
  • Author(s): Kiyoshi Sakai, Akihito Yamamoto#, Kohki Matsubara, Shoko Nakamura, Mami Naruse (#correspondence)
  • Journal Title: The Journal of Clinical Investigation Volume: 122 Pages: 80-90
  • DOI: 10.1172/jci59251
  • Peer Reviewed
• [Journal Article] Effects of implant surface on bone healing around the titanium screw implants in ovariectomized rats (2011)
  • Author(s): Tateishi H, Okamoto Y, Kinoshita K,Hibi H, Uedda M
  • Journal Title: Oral & Craniofaciaal Tissue Engineering Volume: 1(1) Pages: 42-49
  • Peer Reviewed
• [Journal Article] An experimental study of bone healing titanium sc around the crew implants in ovariectomized rats Enhancement of bone healinng by bone marrow stromal cells transsplantation (2011)
  • Author(s): Okamoto Y, Tateishi H, Kinoshita K,Tsuchiya S, Hibi H, Ueda M
  • Journal Title: Implant Dentistry Volume: 220(3) Pages: 236-2245
  • Peer Reviewed
• [Journal Article] Suprapperiosteal transport distraction osteogenesis for reconstructing a segmental defect of the mandible (2011)
  • Author(s): Hibi H, Ueda M
  • Journal Title: Journnal of Oral and Maxillofacial Surgery Volume: 69(3) Pages: 742-746
  • Peer Reviewed
• [Journal Article] Effects of sself-assembling peptide hyddrogel scaffold on bone regeneratioon with recombinant human bone morphogenetic prootein-2 (2011)
  • Author(s): Ikeno M, Hibi H, Kinoshita K, Hattori H, Ueda M
  • Journal Title: Oral & Craniofacial Tissue Engineering Volume: 1(2) Pages: 91-97
  • Peer Reviewed
• [Journal Article] Osteogenic induction of bone marrow-derived stromall cells on simvastatinn-releasing, biodegradable nano- to microscale fiber scafolds (2011)
  • Author(s): Wadagaki R, Mizuno D, Yamawaki-Ogata A,Satake M, Kaneko H, Hagiwara S,Yamamoto N, Narita Y, Hibi H, Ueda M
  • Journal Title: Annals of Biomedical Engineering Volume: 39(7) Pages: 1872-7881
  • Peer Reviewed
• [Journal Article] Stromal cell-derived factor-1 enhances distraction osteogenesis-mediated skeletal tissue regeneratioon through tthe recruitmment of endothelial precursors (2011)
  • Author(s): Fujio M, Yamamoto A, Ando K, Shohara R,Kinoshita K, Kaneko T, Hibi H, Ueda M
  • Journal Title: Bone Volume: 499(4) Pages: 693-700
  • Peer Reviewed
• [Journal Article] Effects of ppermeability of shields with autologous bone grafts on bone augmentation. (2011)
  • Author(s): Ikeno M, Hibi H, Kinoshita K, Hattori H, Ueda M
  • Journal Title: Oral & Craniofacial Tissue Engineering Volume: 1(3) Pages: 198-204
  • Peer Reviewed
• [Journal Article] 歯槽骨の再生医療治療 (2011)
  • Author(s): 日比英晴,上田実
  • Journal Title: 南山堂 Volume: 93(1) Pages: 142-146
• [Journal Article] Effects of implant surface on bone healing around the titanium screw implants in ovariectomized rats (2011)
  • Author(s): Tateishi H
  • Journal Title: Oral & Craniofacial Tissue Engineering Volume: 1 Pages: 42-49
  • Peer Reviewed
• [Journal Article] An experimental study of bone healing around the titanium screw implants in ovariectomized rats (2011)
  • Author(s): Okamoto Y
  • Journal Title: Implant Dentistry Volume: 20 Issue: 3 Pages: 236-245
  • DOI: 10.1097/id.0b013e3182199543
  • Peer Reviewed
• [Journal Article] Osteogenic induction of bone marrow-derived stromal cells on simvastatin-releasing, biodegradable, nano- to microscale fiber scaffolds (2011)
  • Author(s): Wadagaki R
  • Journal Title: Annals of Biomedical Engineering Volume: 39 Issue: 7 Pages: 1872-1881
  • DOI: 10.1007/s10439-011-0327-0
  • Peer Reviewed
• [Journal Article] Stromal cell-derived factor-1 enhances distraction osteogenesis-mediated skeletal tissue regeneration through the recruitment of endothelial precursors (2011)
  • Author(s): Fujo, M., Yamamoto, A#., Ando,Y., Shohara, R., Kinoshita, K., Kaneko, T., Hibi, H., Ueda (#correspondence)
  • Journal Title: Bone Volume: 49 Issue: 4 Pages: 693-700
  • DOI: 10.1016/j.bone.2011.06.024
  • Peer Reviewed
• [Journal Article] Supraperiosteal transport distraction osteogenesis for reconstructinga segmental defect of the mandible (2011)
  • Author(s): Hibi H
  • Journal Title: Journal of Oral and Maxillofacial Surgery Volume: 69 Pages: 742-746
  • Peer Reviewed
• [Journal Article] 歯槽骨の再生医療 (2011)
  • Author(s): 日比英晴
  • Journal Title: 治療 Volume: 93 Pages: 142-146
• [Journal Article] Regulation of the Wnt signaling pathways during cell culture of human mesenchymal stem cells for efficient bone regeneration (2010)
  • Author(s): Katagiri W
  • Journal Title: Oral Science International Volume: 7 Pages: 37-46
  • NAID: 10027680495
  • Peer Reviewed
• [Presentation] The application of atmospheric pressure plasma pretreatment for attaching conditioned medium to dental implant (2013)
  • Author(s): Omori M, Tsuchiya S, Hara K, Fujio M, Kuroda K, Yajima A, Okido M, Hibi H, Ueda M
  • Organizer: 28th Annual Meeting, Academy of Osseointegration
  • Place of Presentation: Tampa, USA
• [Presentation] Preliminary and first-in-human clinical study of novel bone regenerative medicine using the conditioned media from bone marrow derived mesenchymal stem cells (2012)
  • Author(s): Katagiri W, Tateishi H, Osugi M, Shohara R, Inukai T, Kawai T, Hibi H, Hirai T, Ueda M
  • Organizer: 3rd TERMIS World Congress 2012
  • Place of Presentation: Vienna, Austria
  • Year and Date: 2012-09-06
• [Presentation] Conditioned media from bone marrow derived mesenchymal stem cells and adipose derived stem cells enhanced bone regeneration in rat calvarial bone defects (2012)
  • Author(s): Osugi M, Katagiri W, Yoshimi R, Inukai T, Kawai T, Hibi H, Ueda M
  • Organizer: 3rd TERMIS World Congress
  • Place of Presentation: Vienna, Austria
  • Year and Date: 2012-09-06
• [Presentation] Periodontal tissue regeneration with the stem cells cultured conditioned media (2012)
  • Author(s): Kawai T, Katagiri W, Inukai T, Yoshimi R, Osugi M, Hibi H, Ueda M
  • Organizer: 3rd TERMIS World Congress 2012
  • Place of Presentation: Vienna, Austria
  • Year and Date: 2012-09-06
• [Presentation] sFRP-3は骨髄由来間葉系幹細胞を用いた骨再生において骨再生能を上昇させる (2012)
  • Author(s): 大杉将嗣
  • Organizer: 第57回日本口腔外科学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] 培養上清による組織再生／骨延長部の骨形成促進効果の検討 (2012)
  • Author(s): 安藤友二
  • Organizer: 第57回日本口腔外科学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] 種々の幹細胞培養上清由来の成長因子を用いた骨再生医療の開発 (2012)
  • Author(s): 椙村有紀子
  • Organizer: 第57回日本口腔外科学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] 乳歯歯髄幹細胞由来培養上清を用いた脳虚血疾患治療の可能性 (2011)
  • Author(s): 井上崇徳
  • Organizer: 第56回日本口腔外科学会
  • Place of Presentation: 大阪国際会議場(大阪府)
  • Year and Date: 2011-10-22
• [Presentation] 脱落乳歯歯髄由来幹細胞培養上清による細胞増殖能の獲得:Wnt/β-カテニン経路の関連 (2011)
  • Author(s): 吉見涼子
  • Organizer: 第56回日本口腔外科学会
  • Place of Presentation: 大阪国際会議場(大阪府)
  • Year and Date: 2011-10-21
• [Presentation] 幹細胞培養上清由来成長因子による細胞移植をともなわない新規骨再生医療の開発 (2011)
  • Author(s): 片桐渉
  • Organizer: 第56回日本口腔外科学会
  • Place of Presentation: 大阪国際会議場(大阪府)
  • Year and Date: 2011-10-21
• [Presentation] sFRP-3添加骨髄由来間葉系幹細胞を用いた新規培養骨の開発 (2011)
  • Author(s): 河合孝真
  • Organizer: 第56回日本口腔外科学会
  • Place of Presentation: 大阪国際会議場(大阪府)
  • Year and Date: 2011-10-21
• [Presentation] The stem cells cultured conditioned media enhanced bone regeneration (2011)
  • Author(s): Osugi M
  • Organizer: 20th Annual Scientific Meeting of European Association for Osseointegration
  • Place of Presentation: Athens (Greece)
  • Year and Date: 2011-10-12
• [Presentation] Novel xenograft technique using the stem cells cultured conditioned media for bone regeneration (2011)
  • Author(s): Yoshimi, R
  • Organizer: 20th Annual Scientific Meeting of European Association for Osseointegration
  • Place of Presentation: Athens (Greece)
  • Year and Date: 2011-10-12
• [Presentation] 幹細胞培養上清由来成長因子を用いた新規骨・歯周組織再生療法 (2011)
  • Author(s): 犬飼丈晴
  • Organizer: 第54回秋季日本歯周病学会学術大会
  • Place of Presentation: 海峡メッセ下関(山口県)
  • Year and Date: 2011-09-24
• [Presentation] 家兎上顎洞底拳上術モデルにおける幹細胞培養上清由来成長因子による骨形成促進の検討 (2011)
  • Author(s): 木下一彦
  • Organizer: 第41回日本口腔インプラント学会
  • Place of Presentation: 名古屋国際会議場(愛知県)
  • Year and Date: 2011-09-17
• [Presentation] Umbilical cord Wharton's jelly : a new potential cell source of mesenchymal stem cells for wound healing (2011)
  • Author(s): Shohara R
  • Organizer: 9th Annual Meeting of the International Society for stem Cell Research
  • Place of Presentation: Toronto (Canada)
  • Year and Date: 2011-06-15
• [Presentation] Engrafted dental pulp stem cells promoted functional recovery of completely transected rat spinal cord (2011)
  • Author(s): Sakai K
  • Organizer: 9th Annual Meeting of the International Society for stem Cell Research
  • Place of Presentation: Toronto (Canada)
  • Year and Date: 2011-06-15
• [Presentation] 幹細胞培養上清由来成長因子による骨再生能の検討 (2011)
  • Author(s): 大杉将嗣
  • Organizer: 第32回日本炎症・再生医学会
  • Place of Presentation: 京都国際会議場(京都府)
  • Year and Date: 2011-06-02
• [Presentation] 乳歯歯髄幹細胞由来培養上清を用いた脳虚血疾患治療の可能性 (2011)
  • Author(s): 井上崇徳
  • Organizer: 第32回日本炎症・再生医学会
  • Place of Presentation: 京都国際会議場(京都府)
  • Year and Date: 2011-06-02
• [Presentation] 顎顔面領域の骨再生.シンポジウム 骨の再生医療 (2011)
  • Author(s): 日比英晴
  • Organizer: 第65回日本口腔科学会
  • Place of Presentation: タワーホール船堀 東京
  • Year and Date: 2011-04-22
• [Presentation] 顎顔面領域の骨再生 (2011)
  • Author(s): 日比英晴
  • Organizer: 第65回日本口腔科学会
  • Place of Presentation: タワーホール船堀(東京都)(招待講演)
  • Year and Date: 2011-04-22
• [Presentation] Osteoinduction of bone marrow-derived stromal cells on simvastatin-releasing fiber scaffolds (2011)
  • Author(s): 和田垣龍
  • Organizer: 第10回日本再生医療学会
  • Place of Presentation: 京王プラザホテル, 東京都
  • Year and Date: 2011-03-02
• [Presentation] The stem cells cultured conditioned media enhanced bone regeneration (2011)
  • Author(s): Osugi M, Katagiri W, Yoshimi R, Inoue M, Hara K, Inukai T, Hibi H, Ueda M
  • Organizer: 20th Annual Scientific Meeting of European Association for Osseointegration
  • Place of Presentation: Athens, Greece
• [Presentation] Novel xenograft technique using the stem cells cultured conditioned media for bone regeneration (2011)
  • Author(s): Yoshimi R, Katagiri W, Osugi M, Inukai T, Yamamoto A, Hibi H, Ueda M
  • Organizer: 20th Annual Scientific Meeting of European Association for Osseointegration
  • Place of Presentation: Athens, Greece
• [Presentation] Engrafted dental pulp stem cells promoted functional recovery of completely transected rat spinal cord (2011)
  • Author(s): Sakai K, Yamamoto A, Matsubara K, Hibi H, Ueda M
  • Organizer: 9th Annual Meeting of the International Society for Stem Cell Research
  • Place of Presentation: Toronto, Canada
• [Presentation] Umbilical cord Wharton's jelly: a new potential cell source of mesenchymal stem cells for wound healing (2011)
  • Author(s): Shohara R, Takikawa S, Yamamoto A, Hibi H, Kikkawa F, Ueda M
  • Organizer: 9th Annual Meeting of the International Society for Stem Cell Research
  • Place of Presentation: Toronto, Canada.
• [Presentation] A study of bone healing around the titanium screw implants in ovariectomized rats: Can rough surface contribute to the implant stability (2011)
  • Author(s): Tateishi H, Okamoto Y, Kinoshita K, Hibi H, Ueda M
  • Organizer: 26th Annual Meeting, Academy of Osseointegration
  • Place of Presentation: Washington DC, USA
• [Presentation] An experimental study of bone healing around the titanium screw implants in ovariectomized rats: enhancement of bone healing by bone marrow stromal cells transplantation (2011)
  • Author(s): Okamoto Y, Tateishi H, Kinoshita K, Tsuchiya S, Hibi H, Ueda M
  • Organizer: 26th Annual Meeting, Academy of Osseointegration
  • Place of Presentation: Washington DC, USA
• [Presentation] Bone tissue engineering for maxillofacial reconstruction. Special lecture (2010)
  • Author(s): Hibi H
  • Organizer: 49th Congress of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons
  • Place of Presentation: Byeonsan, Korea.
  • Year and Date: 2010-11-05
• [Presentation] Bone tissue engineering for maxillofacial reconstruction (2010)
  • Author(s): Hibi H
  • Organizer: 49th Congress of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons
  • Place of Presentation: ビョンサン, 韓国
  • Year and Date: 2010-11-05
• [Presentation] 骨延長部の骨形成過程におけるSDF-1/CXCR4システムの役割 (2010)
  • Author(s): 藤尾正人
  • Organizer: 第52回歯科基礎医学会
  • Place of Presentation: タワーホール船堀, 東京都
  • Year and Date: 2010-09-21
• [Presentation] Alveolar cleft osteoplasty using qualified tissue-engineered osteogenic material (2010)
  • Author(s): Hibi H, Yamada Y, Ueda M
  • Organizer: 20th Congress of the European Association for Cranio-Maxillofacial Surgery
  • Place of Presentation: Bruges, Belgium.
  • Year and Date: 2010-09-15
• [Presentation] Alveolar cleft osteoplasty using qualified tissue-engineered osteogenic material (2010)
  • Author(s): Hibi H
  • Organizer: 20th Congress of the European Association for Cranio-Maxillofacial Surgery
  • Year and Date: 2010-09-15
• [Presentation] 骨延長部の骨形成過程におけるSDF-1/CXCR4システムの役割 (2010)
  • Author(s): 藤尾正人
  • Organizer: 第31回日本炎症・再生医学会
  • Place of Presentation: 京王プラザホテル, 東京都
  • Year and Date: 2010-08-05
• [Presentation] ヒト臍帯由来の組織再生細胞を用いた骨再生療法の開発 (2010)
  • Author(s): 匠原龍太郎
  • Organizer: 第31回日本炎症・再生医学会
  • Place of Presentation: 京王プラザホテル, 東京都
  • Year and Date: 2010-08-05
• [Presentation] Proliferation of SHED and its relation to Wnt signaling pathway (2010)
  • Author(s): Katagiri W, Yamada Y, Nakamura S, Ito K, Umemura E, Hara K, Hibi H, Ueda M
  • Organizer: 88th International Association for Dental Research General Session & Exhibition
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 2010-07-17
• [Presentation] Cell-based therapy with dental pulp stem cells for bone regeneration (2010)
  • Author(s): Yamada Y, Nakamura S, Ito K, Katagiri W, Umemura E, Hara K, Hibi H, Ueda M
  • Organizer: 88th International Association for Dental Research General Session & Exhibition
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 2010-07-17
• [Presentation] Proliferation of SHED and its relation to Wnt signaling pathway (2010)
  • Author(s): Katagiri W
  • Organizer: 88^<th> International Association for Dental Research General Session & Exhibition
  • Place of Presentation: バルセロナ, スペイン
  • Year and Date: 2010-07-17
• [Presentation] Cell-based therapy with dental pulp stem cells for bone regeneration (2010)
  • Author(s): Yamada Y
  • Organizer: 88^<th> Internatfonal Association for Dental Research General Session & Exhibition
  • Place of Presentation: バルセロナ, スペイン
  • Year and Date: 2010-07-17
• [Presentation] Transplantation of dental pulp stem cells in spinal cord injury (2010)
  • Author(s): Sakai K, Yamamoto A, Hibi H, Yamada Y, Fujio M, Yamagata M, Ueda M
  • Organizer: 88th International Association for Dental Research General Session & Exhibition
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 2010-07-15
• [Presentation] 幹細胞培養上清由来成長因子を用いた新規歯槽骨・歯周組織再生療法
  • Author(s): 犬飼丈晴
  • Organizer: 第11回日本再生医療学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] ヒト臍帯由来間葉系幹細胞による創傷治癒促進効果の検討
  • Author(s): 匠原龍太郎
  • Organizer: 第11回日本再生医療学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] 幹細胞培養上清由来成長因子による骨再生能の検討
  • Author(s): 大杉将嗣
  • Organizer: 第11回日本再生医療学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] sFRP-3は骨髄由来間葉系幹細胞を用いた骨再生において骨形成能を上昇させる
  • Author(s): 河合孝真
  • Organizer: 第11回日本再生医療学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] 乳歯歯髄幹細胞由来培養上清を用いた脳梗塞治療の可能性
  • Author(s): 井上崇徳
  • Organizer: 第11回日本再生医療学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] ヒト臍帯由来間葉系幹細胞による創傷治癒促進効果の検討
  • Author(s): 匠原龍太郎
  • Organizer: 第33回日本炎症・再生医学会
  • Place of Presentation: ホテル日航福岡（福岡市）
• [Presentation] 培養上清による骨延長部の骨形成促進効果の検討
  • Author(s): 安藤友二
  • Organizer: 第33回日本炎症・再生医学会
  • Place of Presentation: ホテル日航福岡（福岡市）
• [Presentation] Preliminary and first-in-human clinical study of novel bone regenerative medicine using the conditioned media from bone marrow derived mesenchymal stem cells
  • Author(s): Katagiri W
  • Organizer: 3rd TERMIS World Congress 2012
  • Place of Presentation: VIenna, Austria
• [Presentation] Conditioned media from bone marrow derived mesenchymal stem cells and adipose derived stem cells enhanced bone regeneration in rat calvarial bone defects
  • Author(s): Osugi M
  • Organizer: 3rd TERMIS World Congress 2012
  • Place of Presentation: VIenna, Austria
• [Presentation] Periodontal tissue regeneration with the stem cells cultured conditioned media
  • Author(s): Kawai T
  • Organizer: 3rd TERMIS World Congress 2012
  • Place of Presentation: VIenna, Austria
• [Presentation] 幹細胞由来成長因子を用いた新規骨・歯周組織再生医療のFirst in human study
  • Author(s): 片桐渉
  • Organizer: 第57回日本口腔外科学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] 幹細胞培養上清由来成長因子による骨・歯周組織再生における作用について
  • Author(s): 河合孝真
  • Organizer: 第57回日本口腔外科学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] ラット歯周組織欠損モデルにおける幹細胞培養上清由来成長因子の歯周組織再生能の検討
  • Author(s): 緒方謙一
  • Organizer: 第57回日本口腔外科学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Presentation] 乳歯歯髄幹細胞由来培養上清を用いた脳虚血疾患治療の可能性
  • Author(s): 服部宇
  • Organizer: 第42回日本創傷治癒学会
  • Place of Presentation: かでる２・７（札幌市）
• [Presentation] ヒト臍帯由来間葉系幹細胞による創傷治癒促進効果の検討
  • Author(s): 匠原龍太郎
  • Organizer: 第42回日本創傷治癒学会
  • Place of Presentation: かでる２・７（札幌市）
• [Presentation] 乳歯歯髄幹細胞由来培養上清を用いたアルツハイマー型認知症治療の可能性
  • Author(s): 見田常幸
  • Organizer: 第12回日本再生医療学会
  • Place of Presentation: パシフィコ横浜（横浜市）
• [Book] 顎骨の再生医療.上田実,朝比奈泉 編;再生医療叢書第8 巻歯学系 (2012)
  • Author(s): 日比英晴
  • Publisher: 朝倉書店
• [Book] 再生医療叢書第8巻歯学系・顎骨の再生医療 (2012)
  • Author(s): 日比英晴
  • Total Pages: 189
  • Publisher: 朝倉書店
• [Book] Applied Tissue Engineering (2011)
  • Author(s): Ito K, Yamada Y, Naiki T, Usami K, Mizuno H, Okada K, Narita Y, Aoki M, Kondo T, Mizuno D, Mase J, Nishiguchi H, Kagami H, Kinoshita K, Hibi H, Nagasaka T, Ueda M: Bone. In: Ueda M, ed.
  • Publisher: InTech
• [Book] Applied Tissue Engineering (2011)
  • Author(s): Ueda M
  • Total Pages: 78
  • Publisher: In Tech
• [Remarks]
  • URL: http://profs.provost.nagoya-u.ac.jp/view/html/100001365_ja.html?k=%E9%A1%8E%E9%A1%94%E9%9D%A2
• [Patent(Industrial Property Rights)] 骨再生用自己組織化ペプチドハイドロゲル (2010)
  • Inventor(s): 上田実,日比英晴,服部宇,池野正幸
  • Industrial Property Rights Holder: 国立大学法人名古屋大学
  • Filing Date: 2010-10-14