Development of the ISVSr(irregular shaking and vibration stimulator) which is new physical therapy, and study of the content effective for the prevention of bone fracture by using it.
| Project/Area Number |
22500484
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Fujita Health University |
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Principal Investigator |
YAMADA Kouji 藤田保健衛生大学, 医療科学部, 准教授 (60278306)
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| Project Period (FY) |
2010-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 骨密度低下 / 骨折予防 / ISVSr / 筋肥大 / 体脂肪 / 骨密度 / マイオカイン / IL-15 / 腰椎 / 骨形態計測 / 骨形成 / 骨吸収 / 振盪 / 振動 / PGC1α / FOXO1 / 大腰筋 |
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| Research Abstract |
The osteoporosis has a massive impact primarily on trabecular bone as a result of the postmenopausal decline in estrogen. The current study used a model of the decrease in bone density in ovariectomized mice to simulate postmenopausal women. Physical therapy to prevent a decrease in bone density was studied via stimulus in the form of rotation of a platform. Analysis of bone histomorphometry revealed lessening of the decrease in bone density of the lumbar vertebrae, a feat that the stimulus from conventional physical therapy had failed to achieve.
With muscles that function as two-joint muscles such as the psoas major, differences exist in muscular hypertrophy, generation and differentiation between origin and insertion sides.
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Report
(5 results)
Research Products
(20 results)
