Exercise therapy for hypertension and diabetes mellitus: involvement of cross-adaptation to stress via inhibition of sympathetic nervous system
| Project/Area Number |
22500609
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Tottori University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Tatsuo 鳥取大学, 医学部, 教授 (60182929)
KOBA Satoshi 鳥取大学, 医学部, 講師 (40565743)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 運動とトレーニング / 慢性運動 / ストレス / 交感神経 / 高血圧 / トレーニング / ノルエピネフリン / SHRラット / 運動療法 / アドレナリン / ノルアドレナリン / 運動 / 糖尿病 |
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| Research Abstract |
We investigated effects of 4-weeks’ running training on the increases in blood pressure (BP) and catecholamine levels induced by a novel stress (immobilization stress) in spontaneously hypertensive rats (SHR). The rats’ sensitivity to exogenously infused norepinephrine (NE) was investigated too. The present results suggest that the stress-induced activation of the sympathetic nervous system and the sensitivity to NE were each attenuated after 4-weeks’ running training, with a consequent reduction in the BP response to a novel stress.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Green odor and depressive-like state in rats: Toward an evidence-based alternative medicine?2011
Author(s)
Watanabe, T., Fujihara, M., Murakami, E., Miyoshi, M., Tanaka, Y., Koba, S. andTachibana, H.
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Journal Title
Behavioural Brain Res
Volume: 224(2)
Issue: 2
Pages: 290-296
DOI
Related Report
Peer Reviewed
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[Journal Article] Protective effects of ginger against aspirin-induced gastric ulcers in rats.2011
Author(s)
Wang, Z., Hasegawa, J., Wang, X.,Matsuda, A., Tokuda, T., Miura, N. and Watanabe, T.
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Journal Title
Yonago Acta medica
Volume: 54
Pages: 11-19
NAID
Related Report
Peer Reviewed
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