A new predicting method and health guidance for the progression of subclinical atherosclerosis using new lifestyle-related serum markers.
| Project/Area Number |
22500663
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Osaka University |
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Principal Investigator |
NISHIDA Makoto 大阪大学, 保健センター, 准教授 (00379273)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 動脈硬化 / 危険因子 / 生活習慣 / 酸化ストレス / アポ蛋白 / 特定健診 / タバコ |
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| Research Abstract |
New serum markers which may indicate carotid atherosclerosis were evaluated with life-style in annual health checkup. ApoB48, a marker for lipids absorbed from intestine, did not correlate with atherosclerosis in all subjects, but significantly correlated in non-obese subjects. It shows apoB48 can be an useful marker detecting atherosclerosis in non-obese subjects. Other new markers including oxidative stress did not associate with progression of atherosclerosis, but with risk factors. Notably, smoking significantly associated progression of atherosclerosis even in a short period. It emphasizes the importance to stop smoking early.
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Report
(4 results)
Research Products
(14 results)
