Empathy for touch in autism spectrum disorder
Project/Area Number |
22591276
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Psychiatric science
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Research Institution | Kyushu University |
Principal Investigator |
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Project Period (FY) |
2010 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Keywords | 脳科学 / 幼児 / 脳磁図 / 体性感覚 / 自閉症 |
Research Abstract |
Two experiments were performed on the cortical processing of empathy-evoking stimuli in the brains of typically-developing (TD) preschool children (3- to 7-years old) and children with autism spectrum disorder (ASD) of the same age. By using magneto-encephalography, we found that TD preschoolers showed more enhanced neural responses to stimulation to their own finger, while they watched stimulation to someone else’ s finger as compared someone else’ s toe. Visual information regarding others thus modulated the children’ s own neural responses to tactile stimulation. In a second experiment, we showed that both TD and ASD children displayed an increased hemodynamic response to whispered speech as compared to normal speech. The increase in the cortical hemodynamic response could reflect the children’ s processing of speaker intent (e.g., confidentiality) in highly-personalized communication. Together , both experiments show that both TD and ASD children are responsive to empathy-related stimuli which require understanding of the feelings of others. Although further study is needed, the cortical responsiveness of ASD children to whisper might be utilized in clinical settings.
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Report
(4 results)
Research Products
(31 results)
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[Journal Article] Altered brain connectivity in 3-to-7-year-old children with autism spectrum disorder.2013
Author(s)
Kikuchi, M., Shitamichi, K., Yoshimura, Y., Ueno, S., et al., Remijn, G.B., Takahashi, T., Suzuki, M., Higashida, H., Minabe, Y.
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Journal Title
Neuroimage: Clinical
Volume: 2
Pages: 394-401
DOI
Related Report
Peer Reviewed
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[Journal Article] A custom Magnetoencephalography device reveals brain connectivity and high reading/decoding ability in children with autism.2013
Author(s)
Kikuchi, M., Yoshimura, Y., Shitamichi, K., Ueno, S., et al., Remijn, G.B., Takahashi, T., Suzuki, M., Higashida, H., Minabe, Y.
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Journal Title
Scientific Reports
Volume: 3
Issue: 1
Pages: 1139-1139
DOI
Related Report
Peer Reviewed
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[Journal Article] Anterior prefrontal hemodynamic connectivity in conscious 3- to 7-year-old children with typical development and autism spectrum disorder.2013
Author(s)
Kikuchi, M., Yoshimura, Y., Shitamichi, K., Ueno, S., et al., Remijn, G.B., Takahashi, T., Suzuki, M., Higashida, H., Minabe, Y.
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Journal Title
PloSONE
Volume: 8
Issue: 2
Pages: 56087-56087
DOI
Related Report
Peer Reviewed
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[Journal Article] Spatiotemporal frequency characteristics of cerebral oscillations during the perception of fundamental frequency contour changes in one-syllable intonation2012
Author(s)
Ueno S, Okumura E, Remijn GB, YoshimuraY, Kikuchi M, Shitamichi K, Nagao K, Mochiduki M, Haruta Y, Hayashi N, Munesue T, Tsubokawa T, Oi M, NakataniH, Higashida H, MinabeY.
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Journal Title
Neurosci Lett
Volume: (in press)
Issue: 2
Pages: 141-146
DOI
Related Report
Peer Reviewed
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[Journal Article] Language performance and auditory evoked fields in 2- to 5-year-old children2012
Author(s)
Yoshimura, Y., Kikuchi, M., Shitamichi, K., Ueno, S., Remijn, G.B., et al
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Journal Title
European Journal of Neuroscience
Volume: 35
Issue: 4
Pages: 644-650
DOI
Related Report
Peer Reviewed
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[Journal Article] Hemodynamic responses to visual stimuli in cortex of adults and 3- to 4-year-old children2011
Author(s)
Remijn, G.B., Kikuchi, M., Yoshimura, Y., Shitamichi, K., Ueno, S., Nagao, K., Munesue, T., Kojima, H., Minabe, Y
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Journal Title
Brain Research
Volume: 1383
Pages: 242-251
Related Report
Peer Reviewed
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[Journal Article] Neurovascular coupling in the human somatosensory cortex: a single trial study2010
Author(s)
Kikuchi, M., Shitamichi, K., Ueno, S., Yoshimura, Y., Remijn, G.B., Nagao, K., Munesue, T., Iiyama, K., Tsubokawa, T., Haruta, Y., Inoue, Y., Watanabe, K., Hashimoto, T., Higashida, H., & Minabe, Y
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Journal Title
Neuroreport
Volume: 21
Pages: 1106-1110
Related Report
Peer Reviewed
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[Journal Article] Neurovascular coupling in the human somatosensory cortex : a single trial study.2010
Author(s)
Kikuchi, M., Shitamichi, K., Ueno, S., Yoshimura, Y., Remijn, G.B., et al.
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Journal Title
NeuroReport
Volume: 21
Pages: 1106-1110
Related Report
Peer Reviewed
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[Presentation] NIRS-measurements of cortical hemodynamic activity in adults and preschool infants in response to static and motion stimuli2010
Author(s)
Remijn, G.B., Kikuchi, M., Yoshimura, Y., Nagao, K., Shitamichi, K., Ueno, S., Kojima, H., & Minabe, Y
Organizer
Clinical Neurophysiology
Place of Presentation
Kobe, Japan
Related Report
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