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Evaluation of neuromuscular disease activity by diffusion tensor imaging

Research Project

Project/Area Number 22591341
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionSapporo Medical University (2011-2013)
Kyushu University (2010)

Principal Investigator

HATAKENAKA Masamitsu  札幌医科大学, 医学部, 教授 (40253413)

Co-Investigator(Kenkyū-buntansha) TAKASHIMA Hiroyuki  札幌医科大学, 医学部, 研究員 (90608738)
TMATSUO Yoshio  九州大学, 大学病院, 助教 (50419595)
OHYAGI Yasumasa  九州大学, 医学研究科, 准教授 (30301336)
SAKAE Nobutaka  九州大学, 大学病院, 助教 (80423523)
NISHIKAWA Kei  九州大学, 大学病院, 診療放射線技師 (30380447)
HONDA Hiroshi  九州大学, 医学(系)研究科(研究院), 教授 (90145433)
Co-Investigator(Renkei-kenkyūsha) SUNAMI Shunya  九州大学, 大学病院, 助教 (80532845)
KAMITANI Takeshi  九州大学, 大学病院, 医員 (20419534)
Project Period (FY) 2010-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
KeywordsMRI / DWI / DTI / Muscle / 骨格筋 / テンソル / 拡散 / ミオパチー
Research Abstract

The fractional anisotropy of myopathy lesion was decreased by 38%, and lambuda 1, 2, and 3 were increased by 59%, 69%, and 79% compared to normal muscles, respectively. These results suggest that parameters related to diffusion tensor imaging are useful for detecting myopathy lesions. However, when comparing absolute parameter values and setting thresholds, some attentions are needed regarding the MR system characteristics.

Report

(5 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (4 results)

All 2013 2012 2010

All Presentation (4 results)

  • [Presentation] 1H MR spectroscopyを用いた代謝物濃度と筋線維角度の関連2013

    • Author(s)
      高島弘幸、宍戸博紀、今村塁、赤塚吉紘、長濱宏史、中西光広、白瀬竜二、畠中正光
    • Organizer
      第41回日本磁気共鳴医学会大会
    • Place of Presentation
      徳島市
    • Related Report
      2013 Final Research Report
  • [Presentation] 1H MRspectroscopyを用いた代謝物濃度と筋線維角度の関連2013

    • Author(s)
      高島弘幸、畠中正光 他
    • Organizer
      日本磁気共鳴医学会
    • Place of Presentation
      徳島市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 足関節角度が下腿筋の1H MR spectroscopyに与える影響2012

    • Author(s)
      高島弘幸
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      京都府京都市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 骨格筋のDTI解析:短縮時・伸長時の比較、骨格筋のtagging解析2010

    • Author(s)
      畠中正光
    • Organizer
      第38回日本磁気共鳴医学会大会筋研究グループミーティング
    • Place of Presentation
      つくば市
    • Related Report
      2013 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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