The role of glial cell in cancer pain, for a new strategy of cancer pain.
Project/Area Number |
22591757
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Anesthesiology/Resuscitation studies
|
Research Institution | National Cancer Center Japan (2011-2012) Research Institute, International Medical Center of Japan (2010) |
Principal Investigator |
SAITO Osamu 独立行政法人国立がん研究センター, 中央病院, 医長 (90344986)
|
Co-Investigator(Renkei-kenkyūsha) |
AOE Tomohiko 千葉大学, 大学院・医学研究院, 准教授 (90311612)
YAMAMOTO Tatsuo 熊本大学, 大学院・医学薬学研究院, 教授 (20200818)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 疼痛管理学(がん性疼痛・緩和医療 / 骨転移 / 疼痛 / 緩和医療 / 鎮痛薬 / グリア / がん性疼痛 / 疼痛管理 / グリア細胞 / サイトカイン |
Research Abstract |
It has been reported that ibudilast can attenuate some kinds of pain, due to its potential as a glial cell modulator. Our study reported it could attenuate bone cancer pain in a mouse model. The result suggests that ibudilast could be useful for the treatment of bone cancer pain.
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Report
(4 results)
Research Products
(6 results)