• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Peripheral Neural regeneration from olfactory mucosa

Research Project

Project/Area Number 22591902
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionNagoya City University

Principal Investigator

HAMAJIMA Yuki  名古屋市立大学, 大学院・医学研究科, 講師 (30343403)

Co-Investigator(Kenkyū-buntansha) HIDA Hideki  名古屋市立大学, 大学院・医学研究科, 教授 (00305525)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords鼻科学 / 神経再生 / 嗅粘膜 / 組織幹細胞
Research Abstract

Many tissue-drived stem cells existed in the Olfactoy fissure of the fetus mouse, cultured that tissue-drived stem cell, transplanted around the facial nerve of the facial nervous paralysis model mouse. As a result, by comparison with the model mouse which heals naturally by transplanting the organizational tissue-drived stem cell of olfactory mucous membrane origin around the paralysis nerve in the facial nervous paralysis model mouse, it was suggested that the period when it requires for facial nervous paralysis improvement is shortened significantly. Concerning paralysis improvement, with the tissue-drived stem cell transplantation mouse and the natural healing group significant difference was not recognized in both groups. Concerning the playback of the nerve, the fact that nervous playback is active is shown, it could recognize the taking in BrdU mainly. Neural stem cells from olfactory mucosa may recover mouse facial nerve palsy better.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (5 results)

All 2012 2011 2010

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (4 results)

  • [Journal Article] 下気道症状を伴う小児急性中耳炎におけるロイコトリエン拮抗薬の効果2010

    • Author(s)
      濱島有喜,中村善久,村上信五
    • Journal Title

      Prog.Med

      Volume: 30(3)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] 名古屋市立大学における唾液腺内視鏡を利用した唾石摘出術2012

    • Author(s)
      濱島有喜
    • Organizer
      第25回日本口腔・咽頭科学会
    • Place of Presentation
      熊本
    • Year and Date
      2012-09-13
    • Related Report
      2012 Final Research Report
  • [Presentation] 名古屋市立大学における唾液腺内視鏡を利用した唾石摘出術2012

    • Author(s)
      濱島有喜
    • Organizer
      第25回日本口腔・咽頭科学会
    • Place of Presentation
      熊本県立劇場(熊本県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Reflux Symptom Index による咽喉頭酸逆流症の診断とプロトンポンプインヒビターによる治療効果 その 22011

    • Author(s)
      濱 島有喜 , 伊地知圭 , 村上信五
    • Organizer
      第23回日本喉頭科学会
    • Place of Presentation
      北海道
    • Year and Date
      2011-04-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Reflux Symptom Indexによる咽喉頭酸逆流症の診断とプロトポンプインヒビターによる治療効果 その22011

    • Author(s)
      濱島有喜
    • Organizer
      第23回日本喉頭科学会
    • Place of Presentation
      旭川グランドホテル(北海道)
    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi