The screening for antibiotic tolerance related genes in peg-biofilm cells of Pseudomonas aeruginosa
| Project/Area Number |
22592040
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
MIYAKE Yoichiro 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (80136093)
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| Co-Investigator(Kenkyū-buntansha) |
HIROTA Katsuhiko 徳島大学, 大学院・ヘルスバイオサイエンス 研究部, 准教授 (60199130)
NEMOTO Ken 徳島大学, 大学院・ヘルスバイオサイエンス 研究部, 助教 (10218274)
MURAKAMI Keiji 徳島大学, 大学院・ヘルスバイオサイエンス 研究部, 助教 (10335804)
ONO Tsuneko 徳島大学, 大学院・ヘルスバイオサイエンス 研究部, 教授 (40035514)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 緑膿菌 / 抗菌薬抵抗性 / バイオフィルム |
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| Research Abstract |
Biofilm bacteria are reported to be tolerant to antibiotics compared to planktonic bacteria. We tried the transposon screening to look for the antibiotic tolerance related genes with biofilm cells.Our results showed that 8 genes for biofilm cells play an important role in antibiotic tolerance.
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Report
(4 results)
Research Products
(9 results)
