Analysis of the temporomandibular joint influeted by Bisphenol A

• Project/Area Number: 22592235
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Kanazawa Medical University
• Principal Investigator: KANEYAMA Keiseki 金沢医科大学, 医学部, 講師 (50329380)
• Co-Investigator(Kenkyū-buntansha): HATTA Toshihisa 金沢医科大学, 医学部, 教授 (20238025) ; SEGAMI Natsuki 金沢医科大学, 医学部, 教授 (40148721)
• Project Period (FY): 2010-04-01 – 2013-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 顎関節 / 環境ホルモン / ビスフェノールA / エストロゲン関連受容体γ / 下顎頭 / 内分泌撹乱物質 / 滑液 / 滑膜 / ビスフェノール / マウス / エストロゲン

Research Abstract

Thepresent study was conducted to investigate the expression of Estrogen related receptor (ERRr)in the temporomandibular joint(TMJ).Fetal mice at 14and 16dpc were fixed in a ormalin and were embeded in parafin at 8um.The TMJ region was examined for the presence of ERRr stained cells.The expression of ERRr of the TMJ region was obsereved in the nuclei of the mandibular

Research Products

• [Journal Article] Internal derangement of the temporomandibular joint with mouth-closing disturbance caused by a thickness of retrodiscal tissue : A case report (2011)
  • Author(s): K.Kaneyama, N.Segami, R.Nishiura, H.Yoshimura
  • Journal Title: J. Oral Maxillofac. Surg Volume: 69 Pages: 1052-1055
  • Peer Reviewed
• [Journal Article] Influences of audio-visual environments on feelings of deliciousness during having sweet foods:an electroencephalogram frequency analysis study (2011)
  • Author(s): H.Yoshimura, M.Honjo, T.Sugai, M.Kawabe, K.Kaneyama, N.Segami, N.Kato
  • Journal Title: Nutr Neurosci Volume: 14(5) Pages: 210-215
  • Peer Reviewed
• [Journal Article] Correlation between stimulation strength and onset time of signal traveling within the neocortical neural circuits under caffeine application (2011)
  • Author(s): H.Yoshimura, M.Honjo, T.Sugai, K.Kaneyama, N. Segami, N.Kato
  • Journal Title: Neurosci Res Volume: 70(4) Pages: 370-375
  • Peer Reviewed
• [Journal Article] Influences of audio-visual environments on feelings of deliciousness durine having sweet foods : an electroencephalogram frequency analysis study (2011)
  • Author(s): Kaneyama K
  • Journal Title: Nutr Neurosci Volume: 14 Pages: 210-215
  • Peer Reviewed
• [Journal Article] Correlation between stimulation strength and onset time of signal traveling within the neocortical neural circuits under caffeine application (2011)
  • Author(s): Kaneyama K
  • Journal Title: Neurosci Res Volume: 70 Pages: 370-375
  • Peer Reviewed
• [Journal Article] Internal derangement of the temporomandibular joint with mouth-closing disturbance caused by a thickness of retrodiscal tissue : a case report (2011)
  • Author(s): Kaneyama K
  • Journal Title: J Oral Maxillofac Surg Volume: 68 Pages: 1052-1055
  • Peer Reviewed
• [Journal Article] Increased levels of soluble cytokine receptors in the synovial fluid of temporomandibular joint disorders in relation to joint effusion on magnetic resonance images (2010)
  • Author(s): K.Kaneyama, N.Segami, H.Yoshimura, M.Honjo, N.Demura
  • Journal Title: J. Oral Maxillofac. Surg Volume: 68 Pages: 1088-1093
  • Peer Reviewed
• [Journal Article] Application of caffeine reveals input frequency-dependent determination of signal-traveling routes between primary and secondary visual cortices in rats (2010)
  • Author(s): H.Yoshimura, T.Sugai, M.Honjo, K.Kaneyama, N.Segami, N.Kato
  • Journal Title: Neurosci Res Volume: 66(1) Pages: 30-36
  • Peer Reviewed
• [Journal Article] Increased levels of soluble cytokine receptors in the synovial fluid of temporomandibular joint disorders in relation to joint effusion on magnetic resonance images. (2010)
  • Author(s): Kaneyama K
  • Journal Title: J Oral Maxillofac Surg Volume: 68 Pages: 1088-1093
  • Peer Reviewed
• [Presentation] マウス顎関節発生におけるエストロゲン関連受容体γの発現について (2013)
  • Author(s): 金山景錫, 八田稔久, 島村英理子, 島田ひろき, 瀬上夏樹
  • Organizer: 第53回日本先天異常学会学術集会
  • Place of Presentation: 大阪
  • Year and Date: 2013-07-21
• [Presentation] 顎関節症に女性ホルモンは関与するか-エストロゲンレセプターの免疫組織学的検討- (2013)
  • Author(s): 金山景錫, 八田稔久, 山本奈央, 瀬上夏樹
  • Organizer: 第67回日本口腔科学会学術集会
  • Place of Presentation: 栃木
  • Year and Date: 2013-05-23
• [Presentation] マウス顎関節発生におけるエストロゲン関連受容体γの発現について (2013)
  • Author(s): 金山景錫
  • Organizer: 第53回日本先天異常学会
  • Place of Presentation: 大阪千里ライフサイエンスセンター（大阪府豊中市）
• [Presentation] 他関節に続発して生じた顎関節ピロリン酸カルシウム(CPPD)結晶沈着症の1例 (2012)
  • Author(s): 金山景錫, 山本奈央, 冨山高史, 瀬上夏樹
  • Organizer: 第55回日本口腔科学会中部地方部会
  • Place of Presentation: 名古屋
  • Year and Date: 2012-12-14
• [Presentation] 顎関節脱臼手術62例の検討 (2012)
  • Author(s): 瀬上夏樹, 金山景錫, 冨山高史
  • Organizer: 第55回日本口腔科学会中部地方部会
  • Place of Presentation: 名古屋
  • Year and Date: 2012-12-14
• [Presentation] われわれが行っているIVSRO(下顎枝垂直矢状分割術) (2012)
  • Author(s): 金山景錫, 瀬上夏樹
  • Organizer: 第37回日本口腔外科学会中部地方会
  • Place of Presentation: 金沢
  • Year and Date: 2012-06-02
• [Presentation] 局麻鎮静下の陳旧性顎関節脱臼手術(関節結節削除+高位下顎頭切除+円板切除) (2012)
  • Author(s): 瀬上夏樹,金山景錫
  • Organizer: 第37回日本口腔外科学会中部地方会
  • Place of Presentation: 金沢
  • Year and Date: 2012-06-02
• [Presentation] 兄弟に発生した舌上皮内癌の2例 (2011)
  • Author(s): 山本奈央, 瀬上夏樹, 金山景錫, 川邊真道
  • Organizer: 日本味と匂学会第45回大会
  • Place of Presentation: 金沢
  • Year and Date: 2011-10-05
• [Presentation] 顎関節症手術における筋突起咬筋処理の適応について‐咀嚼筋・腱膜過形成の合併例は存在するか?- (2011)
  • Author(s): 千葉祐胤, 瀬上夏樹, 金山景錫, 川邊真道
  • Organizer: 第54回日本口腔科学会中部地方部会
  • Place of Presentation: 名古屋
  • Year and Date: 2011-10-01
• [Presentation] ビスフェノールAのマウス下顎頭に及ぼす影響-下顎頭軟骨の層別での検討- (2011)
  • Author(s): 金山景錫
  • Organizer: 第65回NPO法人日本口腔科学会学術集会
  • Place of Presentation: 東京都(タワーホール船堀)
  • Year and Date: 2011-04-22
• [Presentation] ビスフェノールAのマウス下顎頭に及ぼす影響-下顎頭軟骨の層別での検討- (2011)
  • Author(s): 金山景錫, 八田稔久, 吉村弘, 青木秀哲, 小野徹, 瀬上夏樹
  • Organizer: 第65回日本口腔科学会学術集会
  • Place of Presentation: 東京
  • Year and Date: 2011-04-21
• [Presentation] 大胸筋皮弁による口腔癌再建症例の検討 (2010)
  • Author(s): 齋藤多紀, 瀬上夏樹, 金山景錫
  • Organizer: 第53回日本口腔科学会中部地方部会
  • Place of Presentation: 富山
  • Year and Date: 2010-10-02
• [Presentation] ビスフェノールAのマウス下顎頭に及ぼす影響 (2010)
  • Author(s): 金山景錫, 八田稔久, 島村英理子, 島田ひろき, 瀬上夏樹
  • Organizer: 第50回日本先天異常学会学術集会
  • Place of Presentation: 兵庫
  • Year and Date: 2010-07-08
• [Presentation] 女性ホルモン様物質(ビスフェノールA)の胎生期暴露がマウス下顎頭に及ぼす影響 (2010)
  • Author(s): 金山景錫, 八田稔久, 吉村弘, 青木秀哲, 小野徹, 瀬上夏樹
  • Organizer: 第64回日本口腔科学会学術集会
  • Place of Presentation: 札幌
  • Year and Date: 2010-06-24
• [Presentation] 女性ホルモン様物質(ビスフェノールA)の胎生期暴露がマウス下顎頭に及ぼす影響 (2010)
  • Author(s): 金山景錫
  • Organizer: 第50回日本先天異常学会
  • Place of Presentation: 兵庫県淡路市(淡路国際夢舞台)