| Project/Area Number |
22592275
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Orthodontic/Pediatric dentistry
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OSHIMA Shohei 北海道大学, 大学院・歯学研究科, 助教 (00374546)
TAKASAKI Chihiro 北海道大学, 大学院・歯学研究科, 助教 (60451449)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
|
|---|
| Keywords | 中枢神経 / ストレス / 不正咬合 / 咬合の不調和 / 視床下部 / マウス / 成長 / 中枢神経系 / フウス |
|---|
| Research Abstract |
In this study, by using BALB/c-bm/bm mice, the effect of occlusal disharmony on the mechanism of central nervous system related growth and behavior was examined. The release of growth hormone and IGF-I was decreased, resulting to the decrease of growth increase rate. Furthermore, occlusal disharmony during postnatal periodinduced disturbance of circadian rhythm, especially rhythm of feeding behavior.
|
