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Identification of ventilation obstructionsite of OSAS of children by the fluid simulation and construction of the treatment predictive model

Research Project

Project/Area Number 22592292
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionKagoshima University

Principal Investigator

IWASAKI Tomonori  鹿児島大学, 医学部・歯学部附属病院, 講師 (10264433)

Co-Investigator(Kenkyū-buntansha) YAMASAKI Youichi  鹿児島大学, 医歯学総合研究科, 教授 (30200645)
HAYASAKI Haruaki  新潟大学, 医歯学総合研究科, 教授 (60238095)
SAITOH Issei  新潟大学, 医歯学総合研究科, 准教授 (90404540)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords小児 OSAS / 上気道流体シミュレーション / 上顎骨急速拡大 / 鼻腔通気状態 / 舌位 / 咽頭気道体積 / 歯学 / 睡眠時無呼吸症候群 / 小児 / 上顎急速拡大 / 小児OSAS / 小児閉塞性睡眠時無呼吸症候群 / 上顎骨急速拡大装置 / CT
Research Abstract

The fluid mechinical simulation (FMS) was shown to be effectiveto detect a site of the upper airway obstruction. When we planned OSAS treatment, we proved efficacy of the combination of FMS and CBCT to diagnose the obstruction of the upper airway. And we evaluated the effect to nasal cavity ventilation, tongue posture, the pharynx airway volume of the maxillary rapid expansion (RME). RME enlarged pharynx airway with or without the improvement of the nasal cavity aeration state. This effectis effective for OSAS of children. We consider that the above-mentioned results help the construction of the future treatment predictive model.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (30 results)

All 2013 2012 2011 2010

All Journal Article (10 results) (of which Peer Reviewed: 7 results) Presentation (17 results) Book (3 results)

  • [Journal Article] Tongue posture improvement and pharyngeal airway enlargement as secondary effects of rapid maxillary expansion: A cone-beam computed tomography study2013

    • Author(s)
      Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kakuno E, Kanomi R, Hayasaki H, Yamasaki Y
    • Journal Title

      American Journal of Orthodontics and Dentofacial Orthopedics

      Volume: Vol.143 Pages: 235-245

    • Related Report
      2012 Final Research Report
  • [Journal Article] Tongue posture improvement and pharyngeal airway enlargement as secondary effects of rapid maxillary expansion: A cone-beam computed tomography study2013

    • Author(s)
      Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kakuno E, Kanomi R, Hayasaki H, Yamasaki Y
    • Journal Title

      American Journal of Orthodontics and Dentofacial Orthopedics

      Volume: Vol.143 Issue: 2 Pages: 235-245

    • DOI

      10.1016/j.ajodo.2012.09.014

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] aluation of improvement of nasal airway ventilation following rapid maxillary expansion using computational fluid dynamics2012

    • Author(s)
      Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kanomi R, Hayasaki H, Yamasaki Y
    • Journal Title

      American Journal of Orthodontics and Dentofacial Orthopedics

      Volume: Vol.141, No.3 Pages: 269-278

    • Related Report
      2012 Final Research Report
  • [Journal Article] Evaluation of improvement of nasal airway ventilation following rapid maxillary expansion using computational fluid dynamics2012

    • Author(s)
      Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kanomi R, Hayasaki H, Yamasaki Y
    • Journal Title

      American Journal of Orthodontics and Dentofacial Orthopedics

      Volume: Vol.141, No.3 Issue: 3 Pages: 269-278

    • DOI

      10.1016/j.ajodo.2011.08.025

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between mouth opening and upper body movement with intake of different-size food pieces during eating2012

    • Author(s)
      Emi Inada, Issei Saitoh, Kuniko Nakakura-Ohshima, Tomoaki Maruyama, Tomonori Iwasaki, Daisuke Murakami, Miyuki Tanaka, Haruaki Hayasaki, Youichi Yamasaki
    • Journal Title

      Archives of Oral Biology

      Volume: 57(3) Issue: 3 Pages: 307-313

    • DOI

      10.1016/j.archoralbio.2011.08.023

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of upper airway obstruction in Class II children using fluid-mechanical simulation2011

    • Author(s)
      Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kanomi R, Hayasaki H, Yamasaki Y
    • Journal Title

      Am J Orthod Dentofacial Orthop

      Volume: Vol.139, No.2

    • Related Report
      2012 Final Research Report
  • [Journal Article] Evaluation of upper airway obstruction in Class II children using fluid-mechanical simulation.2011

    • Author(s)
      Tomonori Iwasaki
    • Journal Title

      American Journal of Orthodontics and Dentofacial Orthopedics

      Volume: 139(2)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pharyngeal Airway in Children with Prognathism and Normal Occlusion2011

    • Author(s)
      Yoshihiko Takemoto
    • Journal Title

      The Angle Orthodontist

      Volume: 81(1) Pages: 77-82

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Head Motion May Help Mouth Openig in Children.2011

    • Author(s)
      Kuniyasu Kuroda
    • Journal Title

      Archives of Oral Biology

      Volume: 56(1) Pages: 102-107

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of Labial-Closure Strength in Preschool Children.2010

    • Author(s)
      Atsushi Fukami
    • Journal Title

      Journal of Craniomandibular Practice

      Volume: 28(4) Pages: 232-237

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Detection of specific obstruction sites using fluid-structure interaction analysis in children with upper airway obstruction2012

    • Author(s)
      Iwasaki T, Saitoh I, Harada M, Miyashita K, Matsune S, Takemoto Y, Fukami A, Sato H, Inada E, Hasegawa H, Kakuno E, Kanomi R, Hayasaki H, Kurono Y, Yamasaki Y
    • Organizer
      THE 7TH ASIAN SLEEP RESEAR SOCIETY CONGRESS
    • Place of Presentation
      Taipei
    • Year and Date
      2012-11-30
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] CBCTを用いた上顎骨側方急速拡大による舌位改善と咽頭気道拡大の評価2012

    • Author(s)
      岩崎智憲,嘉ノ海龍三,武元嘉彦,齊藤一誠,覚野恵梨子,早崎治明,山崎要一
    • Organizer
      第71回日本矯正歯科学会
    • Place of Presentation
      盛岡市
    • Year and Date
      2012-09-28
    • Related Report
      2012 Final Research Report
  • [Presentation] 上気道流体シミュレーションを用いた上顎骨急速拡大による歯科治療前後の吸気時咽頭気道圧の評価2012

    • Author(s)
      岩崎智憲, 齊藤一誠, 原田みずえ, 宮下圭一, 松根彰志, 武元嘉彦, 深水 篤, 佐藤秀夫, 稲田絵美, 長谷川大子, 覚野恵梨子,嘉ノ海龍三, 早崎治明, 黒野祐一, 山崎要一
    • Organizer
      第37回日本睡眠学会
    • Place of Presentation
      横浜市
    • Year and Date
      2012-06-29
    • Related Report
      2012 Final Research Report
  • [Presentation] Improving tongue posture and pharynx airway as a side effect of rapid maxillary expansion in children: A cone-beam computed tomography study2012

    • Author(s)
      Iwasaki T, Saitoh I, Kanomi R, Hayasaki H, Yamasaki Y
    • Organizer
      American Association of Orthodontists (AAO) 112th Annual Session
    • Place of Presentation
      Honolulu
    • Year and Date
      2012-05-03
    • Related Report
      2012 Final Research Report
  • [Presentation] Analysis of upper airway obstruction in Class II children using fluid-mechanical simulation, the 8th Biennial Conference of the Pediatric Dentistry Association of Asia (PDAA)2012

    • Author(s)
      Yamasaki Y, Iwasaki T, Saitoh I, Takemoto Y, Inada E, Kakuno E, Kanomi R, Hayasaki H
    • Organizer
      The 5 finalists of Scientific competition in Research Poster Session.
    • Place of Presentation
      Sanur Paradisw Plaza Hotel, Bali in Indonesia
    • Related Report
      2012 Final Research Report
  • [Presentation] 上気道流体シミュレーションを用いた上顎骨急速拡大による歯科治療前後の吸気時咽頭気道圧の評価, (ベストプレゼンテーション賞 受賞)2012

    • Author(s)
      岩崎智憲
    • Organizer
      第37回日本睡眠学会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] 上気道流体シミュレーションを用いた睡眠時無呼吸症候群への臨床応用2011

    • Author(s)
      岩崎智憲
    • Organizer
      Phoenics User Conference 2011
    • Place of Presentation
      東京都・東京国際フォーラム(招待講演)
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 閉塞性睡眠時無呼吸症候群への上気道流体シミュレーションの臨床応用2011

    • Author(s)
      岩崎智憲,齊藤一誠,早崎治明,山崎要一
    • Organizer
      第27回「歯科医学を中心とした総合的な研究を推進する集い」
    • Place of Presentation
      東京都千代田区・日本歯科医師会館
    • Year and Date
      2011-01-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 閉塞性睡眠時無呼吸症候群への上気道流体シミュレーションの臨床応用2011

    • Author(s)
      岩崎智憲
    • Organizer
      第27回「歯科医学を中心とした総合的な研究を推進する集い」
    • Place of Presentation
      東京都千代田区
    • Year and Date
      2011-01-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] Detection of specific obstruction sites using fluid-structure interaction analysis in children with obstructive sleep apnea syndrome2011

    • Author(s)
      Iwasaki T, Saitoh I, Harada M, Miyashita K, Matsune S, Takemoto Y, Inada E, Kanomi R, Hayasaki H, Kurono Y, Yamasaki Y
    • Organizer
      World Sleep 2011
    • Place of Presentation
      Kyoto, Japan, ICC Kyoto
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 上気道流体シミュレーションの顎骨延長術への臨床応用2011

    • Author(s)
      近藤俊, 他
    • Organizer
      第70回日本矯正歯科学会大会&第4回国際会議
    • Place of Presentation
      名古屋市・名古屋国際会議場(大会優秀発表賞受賞)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 反対咬合を主訴に来院し、閉塞性睡眠時無呼吸症候群を認めた症例2011

    • Author(s)
      武元嘉彦, 他
    • Organizer
      第30回日本小児歯科学会中四国地方会大会および総会,第29回日本小児歯科学会九州地方会大会および総会
    • Place of Presentation
      北九州市・九州歯科大学
    • Related Report
      2011 Annual Research Report
  • [Presentation] CBCTを応用した3次元気道構築と流体シミュレーションによる通気機能病態診断の試み2010

    • Author(s)
      岩崎智憲
    • Organizer
      日本歯科医学会プロジェクト研究
    • Place of Presentation
      東京都品川区
    • Year and Date
      2010-08-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 上気道流体シミュレーションを用いた小児閉塞性睡眠時無呼吸症候群の通気障害部位の特定方法について2010

    • Author(s)
      岩崎智憲, 早崎治明, 嘉ノ海龍三, 武元嘉彦, 齊藤一誠, 松根彰志, 黒野祐一, 山崎要一
    • Organizer
      第48回日本小児歯科学会大会
    • Place of Presentation
      名古屋市
    • Related Report
      2012 Final Research Report
  • [Presentation] Evaluation of upper airway obstruction in Class II children using fluid-mechanical simulation2010

    • Author(s)
      Iwasaki T, Kanomi R, Hayasaki H,Yamasaki Y
    • Organizer
      American Association of Orthodontists (AAO) 110th Annual Session
    • Place of Presentation
      Washington DC
    • Related Report
      2012 Final Research Report
  • [Presentation] 上顎急速拡大前後の鼻腔通気状態に関する流体シミュレーション評価2010

    • Author(s)
      岩崎智憲
    • Organizer
      第69回日本矯正歯科学会
    • Place of Presentation
      横浜(大会優秀発表賞受賞)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 上気道流体シミュレーションを用いた小児閉塞性睡眠時無呼吸症候群の通気障害部位の特定方法について2010

    • Author(s)
      岩崎智憲
    • Organizer
      第48回日本小児歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2010 Annual Research Report
  • [Book] 小児歯科はいま、成育医療へ;2011年デンタルダイヤモンド増刊号2011

    • Author(s)
      岩崎智憲(分担)
    • Publisher
      デンタルダイヤモンド社,東京
    • Related Report
      2011 Annual Research Report
  • [Book] 小児歯科学第4版2011

    • Author(s)
      岩崎智憲
    • Publisher
      医歯薬出版
    • Related Report
      2010 Annual Research Report
  • [Book] 小児歯科はいま、成育医療へ2011

    • Author(s)
      岩崎智憲
    • Publisher
      デンタルダイヤモンド社
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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