Prototype of bio-membrane/semiconductor active device

Research Project

Project/Area Number	22656007
Research Category	Grant-in-Aid for Challenging Exploratory Research
Allocation Type	Single-year Grants
Research Field	Applied materials science/Crystal engineering
Research Institution	Nagoya University
Principal Investigator	UJIHARA Toru 名古屋大学, 工学研究科, 教授 (60312641)
Co-Investigator(Renkei-kenkyūsha)	TERO Ryugo 豊橋技術科学大学, エレクトロニクス先端融合研究所, 助教 (40390679)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥3,590,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥390,000) Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2010: ¥1,900,000 (Direct Cost: ¥1,900,000)
Keywords	脂質二重膜 / 半導体デバイス / 相分離構造
Research Abstract	In this study, as a demonstration of the basic motion of a biomembrane/semiconductor active device, we performed the formation of the phase separation domains at arbitrary positions by light irradiation. In order to achieve patterning especially by laser light irradiation, fluorescence lipid composition and diffusion coefficient were optimized. Furthermore, in order to investigate the possibility of a protein aggregation, Annexin V was introduced. As a result, the fluorescence due to the Annexin V were observed at the same positions of domain structure. It suggested that the protein aggregation control by domain control was possible.