Analysis of molecular mechanisms regulating specific gene expression of sex pheromone receptor genes in the silkmoth
| Project/Area Number |
22688004
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied entomology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SAKURAI Takeshi 東京大学, 先端科学技術研究センター, 特任講師 (20506761)
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| Project Period (FY) |
2010-04-01 – 2013-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
Fiscal Year 2012: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2011: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2010: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Keywords | 昆虫 / 遺伝子 / 発現制御 / 性フェロモン受容体 / カイコガ |
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| Research Abstract |
The purpose of this study is to understand molecular mechanisms underlying highly specific gene expression of sex pheromone receptor genes in the silkmoth Bombyx mori. in vivo promoter assay of BmOR1 gene that encodes the sex pheromone receptor for the main pheromone component of the silkmoth, bombykol, indicated that 0.3 kb upstream regulatory sequences of BmOR1 can appropriately induce reporter gene expression in bombykol sensitive olfactory receptor neurons in the male antennae. Analysis of this upstream region revealed the presence of a potential binding site of doublesex protein that is a transcription factor involved in sex determination in the silkmoth. These results provide important information to unrabel the mechanism of sex pheromone receptor gene regulation in the silkmoth.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] Pheromone responsiveness threshold depends on temporal integration by antennal lobe projection neurons2013
Author(s)
Tabuchi M, Sakurai T, Mitsuno H, Namiki S, Minegishi R, Shiotsuki T, Uchino K, Sezutsu H, Tamura T, Haupt SS, Nakatani K, Kanzaki R
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Journal Title
Proceedings of the National Academy of Sciences USA
Volume: 110(38)
Pages: 15455-15460
Related Report
Peer Reviewed
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[Journal Article] Pheromone responsiveness threshold depends on temporal integration by antennal lobe projection neurons2013
Author(s)
Tabuchi M, Sakurai T, Mitsuno H, Namiki S, Minegishi R, Shiotsuki T, Uchino K, Sezutsu H, Tamura T, Haupt SS, Nakatani K, Kanzaki R
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Journal Title
Proceedings of the National Academy of Sciences of USA
Volume: 110(38)
Issue: 38
Pages: 15455-60
DOI
Related Report
Peer Reviewed
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