| Project/Area Number |
22790615
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | University of Toyama |
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Principal Investigator |
FUJIMOTO Makoto 富山大学, 大学院・医学薬学研究部(医学), 助教 (30377337)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | メタボリックシンドローム / 桂枝茯苓丸 / 非アルコール性脂肪性肝障害 / NAFLD / NASH / 漢方 / pioglitazone |
|---|
| Research Abstract |
In this study, to accumulate the scientific evidences about the effects of traditional medicines on NAFLD, we investigated the effects of Keishibukuryogan and pioglitazone on NAFLD mouse model induced by the subcutaneous injection treatment of monosodium glutamate. Both Keishibukuryougan and pioglitazone did not show the preventive effect for NAFLD. Sterile environment breeding may provoke these results.
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