| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
We have developed a novel computed tomography lymphography(CTLG) by transbronchial injection of a water-soluble extracellular CT contrast agent of iopamidol to identify sentinel nodes(SNs) in preoperative non-small cell lung cancer(NSCLC) patients. Twenty-one patients with clinical stage I NSCLC were enrolled in the study. The ultrathin bronchoscope accessed targeted bronchus, and iopamidol was delivered into the peritumoral area in all patients without any complications. SNs were identified in 20 of 21 patients(95. 2%), and the average number of SNs was 1. 7(range : 1-4). Pathologic examination revealed metastatic lymph nodes in two patients. These metastatic lymph nodes were included in the SNs. CTLG by transbronchial injection of iopamidol was a safe and useful method to identify SNs in preoperative patients with NSCLC.
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