Basic study on aimed at relief of neuropathic pain, and the elucidation of the mechanisms underlying the new pain control system of the docosahexaenoic acid
Project/Area Number |
22791459
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Anesthesiology/Resuscitation studies
|
Research Institution | Kobe Gakuin University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 疼痛管理学 / 長鎖脂肪酸受容体 / GPR40 / 抗侵害作用 / ドコサヘキサエン酸 / オピオイオド神経系 / 内因性オピオイド |
Research Abstract |
We demonstrated that DHA-induced antinociception via β-endorphin release may be mediated through GPR40 signaling in the supraspinal area, and may provide valuable information on a novel therapeutic approach for pain control.
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Report
(3 results)
Research Products
(29 results)