| Project/Area Number |
22791565
|
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| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
|
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
|
|---|
| Keywords | VASOHIBIN / 鼻腔 / Vasohibin-1 / 嗅上皮 |
|---|
| Research Abstract |
Vasohibin-1 has been reported as a novel functional molecules which negatively regulated angiogenesis. It was suggested by our preliminary experiment that Vasohibin-1 might be involved in the expression of the olfactory receptor, so we verified the expression of Vasohibin-1 in the nasal tissue. Although we confirmed Vasohibin-1 expression in mouse nasal tissue by RT-PCR and immunostaining method, it was not observed on olfactory cells but endothelial cells. The result which supported our hypothesis of the regulation the olfactory receptor by Vasohibin-1 was not obtained.
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