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evaluationofeffectivenessoftheobjectiveexaminationforautism indeafchildren

Research Project

Project/Area Number 22791642
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research Institution公益財団法人先端医療振興財団 (2012)
Foundation for Biomedical Research and Innovation (2010-2011)

Principal Investigator

YAMAZAKI Hiroshi  公益財団法人先端医療振興財団, 診療部, 研究員 (80536243)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords人工内耳 / 自閉症 / ASD / autistic spectrum disorder(ASD) / autistic spectrum disorder (ASD)
Research Abstract

Approximately 25% of congenital sensorineural hearing loss is caused by congenital cytomegalovirus (CMV) infection, which also affects higher brain functions. We evaluated cochlear implant (CI) outcomes of deaf children with congenital CMV infection, some of which suffered from pervasive developmental disorders (PDD) including autistic disorder. Incases with out PDD, the postoperative CI- aided language development is significantly associated with their preoperative cognitive development,but incases with PDD, their CI- aided language development was much lower than those expected from their cognitive development. These data suggests that mechanism of language retardation in PDD might be d fferent from those in other higher brain dysfunctions including mental retardation.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (40 results)

All 2013 2012 2011 2010

All Journal Article (9 results) (of which Peer Reviewed: 3 results) Presentation (30 results) Book (1 results)

  • [Journal Article] 内耳奇形を伴う小児人工内耳症例の術後成績2012

    • Author(s)
      諸頭三郎、山崎博司、内藤泰、眞鍋朋子、山本輪子、藤原敬三、篠原尚吾
    • Journal Title

      Audiology Japan

      Volume: 55(1) Pages: 68-76

    • NAID

      10030745040

    • Related Report
      2012 Final Research Report
  • [Journal Article] Cochlear implantation in children with congenital cytomegalovirus infection accompanied by psycho-neurological disordes.2012

    • Author(s)
      Yamazaki H, Yamamoto R, Moroto S, Yamazaki T, Fujiwara K, Nakai M, Ito J, Naito Y
    • Journal Title

      Acta Oto-Laryngologica

      Volume: 132 Pages: 420-427

    • Related Report
      2012 Final Research Report
  • [Journal Article] Cochlear implantation in children with congenital cytomegalovirus infection accompanied by psycho-neurological disordes2012

    • Author(s)
      Yamazaki H
    • Journal Title

      Acta Oto-Laryngologica

      Volume: 132 Pages: 420-427

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cochlear implantation in children with congenital cytomegalovirus infection accompanied by psycho-neurological disorders2012

    • Author(s)
      Yamazaki H, Yamamoto R, Motorou S, et al
    • Journal Title

      Acta Oto-Laryngologica

      Volume: 132 Pages: 420-427

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 当科における優性遺伝形式をとる遺伝性難聴症例の検討2011

    • Author(s)
      内藤泰、山崎博司
    • Journal Title

      厚生労働科学研究費補助金軟治性疾患克服研究事業優性遺伝形式をとる遺伝性難聴に関する調査研究 平成22年度総括・分担研究報告書 研究代表者 宇佐美真一

      Pages: 48-51

    • Related Report
      2012 Final Research Report
  • [Journal Article] Reversible cochlear disorders with normal vestibular functions in three cases with Wegener's granulomatosis2011

    • Author(s)
      Yamazaki H, Fujiwara K, Shinohara S, Kikuchi M, KanazawaY ,Kurihara R, Kishimoto I, Naito Y
    • Journal Title

      Auris NasusL arynx

      Volume: 39 Pages: 236-240

    • Related Report
      2012 Final Research Report
  • [Journal Article] Reversible cochlear disorders with normal vestibular functions in three cases with Wegener's granulomatosis2011

    • Author(s)
      Yamazaki H, Fujiwara K, Shinohara S, et al
    • Journal Title

      Auris Nasus Larynx

      Volume: 39 Pages: 236-240

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 抗菌薬動脈注射が奏功した頭蓋底骨髄炎合併悪性外耳道炎の2例2010

    • Author(s)
      山崎博司、内藤泰、藤原敬三、菊地正弘、十名洋介、金沢佑治、栗原理紗
    • Journal Title

      日耳鼻

      Volume: 113 Pages: 851-855

    • NAID

      10029380510

    • Related Report
      2012 Final Research Report
  • [Journal Article] Brain imaging findings in cochlear implant users2010

    • Author(s)
      Naito Y, Fujiwara K, Yamazaki H, ShinoharaS, Kikuchi M, Moroto S, Yamamoto R, Manabe T
    • Journal Title

      2010年ソウル大学医学部付属病院人工内耳シンポジウム1000患者記念

      Pages: 19-21

    • Related Report
      2012 Final Research Report
  • [Presentation] cochlear implant outcomes in cases with cochlear nerve deficiency2013

    • Author(s)
      Yamazaki H
    • Organizer
      IFOS
    • Place of Presentation
      Soul, Korea
    • Related Report
      2012 Annual Research Report
  • [Presentation] 両側亜急性進行性感音難聴の26例2012

    • Author(s)
      岸本逸平,山崎博司,内藤 泰,篠原尚吾,藤原敬三,菊地正弘,栗原理紗,原田博之
    • Organizer
      第170回日耳鼻兵庫県地方部会
    • Place of Presentation
      尼崎市
    • Year and Date
      2012-04-01
    • Related Report
      2012 Final Research Report
  • [Presentation] 当科における優性遺伝形式遺伝性難聴の検討2012

    • Author(s)
      山崎博司、内藤泰
    • Organizer
      平成23年度 厚生労働省科学研究費補助金 難治性疾患克服研究事業 優性遺伝形式をとる遺伝性難聴に関する調査研究. Usher症候群に関する調査研究
    • Place of Presentation
      東京都
    • Year and Date
      2012-02-04
    • Related Report
      2012 Final Research Report
  • [Presentation] 当科におけるUsher症候群の検討2012

    • Author(s)
      山崎博司、内藤泰
    • Organizer
      平成23年度 厚生労働省科学研究費補助金 難治性疾患克服研究事業 優性遺伝形式をとる遺伝性難聴に関する調査研究. Usher症候群に関する調査研究
    • Place of Presentation
      東京都
    • Year and Date
      2012-02-04
    • Related Report
      2012 Final Research Report
  • [Presentation] HRCT-based prediction for CI outcomes of cases with inner ear/Internal auditory canal malfromations2012

    • Author(s)
      Yamazaki H, Koyasu S, Moroto S, Yamamoto R, Yamazaki T, Fujiwara K, Naito Y
    • Organizer
      The 9th International Conference on Cholesteatom and Ear Surgery
    • Place of Presentation
      Nagasaki, Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] Outcomes of cases with temporal bone malformations2012

    • Author(s)
      Yamazaki H, Koyasu S, Moroto S, Yamamoto R, Yamazaki T, Fujiwara Y, Naito Y
    • Organizer
      AAO-HNSF 116th Annual Meeting & OTO EXPO in Washington, DC, U. S. A
    • Place of Presentation
      Washington, DC, U. S. A
    • Related Report
      2012 Final Research Report
  • [Presentation] Etiology of 26 cases with progressive bilateral SNHL2012

    • Author(s)
      Kishimoto I, Yamazaki H, Naito Y, Shinohara S, Fujiwara K, Kikuchi M, Kurihara R
    • Organizer
      AAO-HNSF 116th Annual Meeting & OTO EXPO in Washington, DC, U. S. A
    • Place of Presentation
      Washington, DC, U. S. A
    • Related Report
      2012 Final Research Report
  • [Presentation] 小児内耳・内耳道奇形例の人工内耳マッピングにおけるEABRの有用性2012

    • Author(s)
      諸頭三郎,山崎博司,山本輪子,眞鍋朋子,藤原敬三,篠原尚吾,内藤 泰
    • Organizer
      第57回日本聴覚医学会
    • Place of Presentation
      京都市
    • Related Report
      2012 Final Research Report
  • [Presentation] HRCT-based prediction for CI outcomes of cases with inner ear / Internal auditory canal malfromations2012

    • Author(s)
      Yamazaki H
    • Organizer
      The 9th International Conference on Cholesteatom and Ear Surgery
    • Place of Presentation
      Nagasaki, Japan
    • Related Report
      2012 Annual Research Report
  • [Presentation] Outcomes of cases with temporal bone malformations2012

    • Author(s)
      Yamazaki H
    • Organizer
      AAO-HNSF 116th Annual Meeting & OTO EXPO
    • Place of Presentation
      Washington, DC, U.S.A
    • Related Report
      2012 Annual Research Report
  • [Presentation] 人工内耳埋め込み術を施行したauditory neuropathyの一例2011

    • Author(s)
      山崎博司、内藤 泰、篠原尚吾、藤原敬三、菊地正弘、金沢佑治、栗原理紗、岸本逸平、原田博之
    • Organizer
      第168回日耳鼻兵庫県地方部会(耳鼻咽喉科・頭頸部外科学会)
    • Place of Presentation
      神戸市
    • Year and Date
      2011-07-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 先天性サイトメガロウイルス感染小児の人工内耳術後成績2011

    • Author(s)
      山本輪子、諸頭三郎、山崎博司、眞鍋朋子、藤原敬三、篠原尚吾、菊地正弘、栗原理紗、金沢佑治、岸本逸平、原田博之、内藤泰
    • Organizer
      第167日耳鼻兵庫県地方部会
    • Place of Presentation
      姫路市
    • Year and Date
      2011-03-27
    • Related Report
      2012 Final Research Report
  • [Presentation] Cochlear Inlplantation in Children with Congenital Cytomegalovirus Infection Accompanied by Neurodevelopmental Disorders2011

    • Author(s)
      Yamazaki H, Yamamoto R, Moroto S, Yamazaki T, Fujiwara K, Nakai M, Ito J, Naito Y
    • Organizer
      COLLEGIUM Oto-Rhino-Laryngologium Amicitiae Sacrum
    • Place of Presentation
      Bruges-Belgium
    • Related Report
      2012 Final Research Report
  • [Presentation] Cochlear implantation in three children with common cavity deformity: usefulness of a wide labyrinthotomy procedure and an intraoperative EABR2011

    • Author(s)
      Yamazaki H
    • Organizer
      The 8th Asia Pacific Synlposium on Cochlear Inlplant and Related Sciences (APSCI 2011)
    • Place of Presentation
      Daegu, Korea
    • Related Report
      2012 Final Research Report
  • [Presentation] Cochlear implantation in children with congenital cytomegalovirus infection accompanied by neurodevelopmental disorders2011

    • Author(s)
      Yamazaki H, Yamamoto R, Moroto S, Yamazaki T, Fujiwara K, Nakai M, Ito J, Naito Y
    • Organizer
      11th Japan-Taiwan Conference on Otolaryngology - Head and Neck Surgery 2011
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] 人工内耳手術症例における内耳および内耳道奇形画像の検討2011

    • Author(s)
      子安翔、山崎博司、内藤泰、上田浩之、伊藤亨
    • Organizer
      第47回日本医学放射線学会秋季大会
    • Place of Presentation
      下関市
    • Related Report
      2012 Final Research Report
  • [Presentation] 先天性サイトメガロウイルス感染小児の人工内耳術後成績2011

    • Author(s)
      山本輪子、諸頭三郎、山崎博司、眞鍋朋子、藤原敬三、篠原尚吾、内藤 泰
    • Organizer
      第56回日本聴覚医学会
    • Place of Presentation
      福岡市
    • Related Report
      2012 Final Research Report
  • [Presentation] 蝸牛神経描出不良例での人工内耳埋め込み術における術中EABRの有用性2011

    • Author(s)
      山崎博司、内藤 泰、藤原敬三、菊地正弘、栗原理紗、岸本逸平
    • Organizer
      第21回日本耳科学会
    • Place of Presentation
      沖縄県宜野湾市
    • Related Report
      2012 Final Research Report
  • [Presentation] Cochlear Implantation in Children with Congenital Cytomegalovirus Infection Accompanied by Neurodevelopmental Disorders2011

    • Author(s)
      Yamazaki H
    • Organizer
      COLLEGIUM-Oto-Rhino-Laryngologium Amicitiae Sacrum
    • Place of Presentation
      Bruges-Belgium
    • Related Report
      2011 Annual Research Report
  • [Presentation] Cochlear implantation in three children with common cavity deformity : usefulness of a wide labyrinthotomy procedure and an intraoperative EABR2011

    • Author(s)
      Yamazaki H
    • Organizer
      The 8th Asia Pacific Symposium on Cochlear Implant and Related Sciences
    • Place of Presentation
      Daegu, Korea
    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
  • [Presentation] Cochlear Implantation in Children with Congenital Cytomegalovirus Infection Accompanied by Neurodevelopmental Disorders2011

    • Author(s)
      Yamazaki H
    • Organizer
      11th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery 201
    • Place of Presentation
      Kobe Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] Cochlear Implantation in Children with Congenital Cytomegalovirus Infection Accompanied by Neurodevelopmental Disorders2011

    • Author(s)
      Yamazaki H
    • Organizer
      COLLEGIUM Oto-Rhino-Laryngologium Amicitiae Sacrum
    • Place of Presentation
      Bruges-Belgium
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cochlear Implantation in Children with Congenital Cytomegalovirus Infection Accompanied by Neurodevelopmental Disorders2011

    • Author(s)
      Yamazaki H
    • Organizer
      11th Japan-Taiwan Conference on Otolaryngology Head and Neck Surgery 201
    • Place of Presentation
      Kobe Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] 人工内耳埋め込み術を施行したauditory neuropathyの1例2010

    • Author(s)
      山崎博司
    • Organizer
      第17回京都耳鼻咽喉科研究会
    • Place of Presentation
      京都市
    • Year and Date
      2010-12-04
    • Related Report
      2012 Final Research Report
  • [Presentation] Cochlear implantation in a child with CHARGE syndrome : diagnostic and surgical implications2010

    • Author(s)
      Naito Y, Fujiwara K, Yamazaki H, Fujiki N, Ito J, Moroto S, ManabeT, Yamamoto R
    • Organizer
      COLLEGIUM OTO-RHINO-LARYNGOLOGICUM AMICITIAE SACRUM
    • Place of Presentation
      BUDAPEST, HUNGARY
    • Related Report
      2012 Final Research Report
  • [Presentation] Inner Ear Disorders Observed in ANCA-associated Vasculitis2010

    • Author(s)
      Yamazaki H, Naito Y, Shinohara S, Fujiwara K, Kikuchi M, Kanazawa Y, Kurihara R, Kishimoto I
    • Organizer
      Sixth International Symposium on Meniere's Disease and Inner Ear Disorders
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] ステロイド依存性の両側混合性難聴を初発症状としたANCA関連血管炎の3例2010

    • Author(s)
      山崎博司、内藤 泰、篠原尚吾、藤原敬三、菊地正弘、十名洋介、金沢佑治、栗原理紗
    • Organizer
      第72回耳鼻咽喉科臨床学会
    • Place of Presentation
      倉敷市
    • Related Report
      2012 Final Research Report
  • [Presentation] 小児内耳・内耳道奇形症例における人工内耳手術の検討2010

    • Author(s)
      山崎博司、内藤 泰、篠原尚吾、藤原敬三、菊地正弘、金沢佑治、栗原理紗、岸本逸平
    • Organizer
      第20回日本耳科学会
    • Place of Presentation
      愛媛県
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] 内耳奇形を伴った小児人工内耳症例の術後成績2010

    • Author(s)
      諸頭三郎、山崎博司、内藤 泰、眞鍋朋子、山本輪子、藤原敬三、篠原尚吾
    • Organizer
      第55回日本聴覚医学会
    • Place of Presentation
      奈良市
    • Related Report
      2012 Final Research Report
  • [Presentation] 当院救急外来における3年間のめまい症例の検討2010

    • Author(s)
      山崎博司、十名洋介、蛯名智正、内藤 泰、篠原尚吾、藤原敬三、菊地正弘、金沢佑治、栗原理紗、岸本逸平、有吉孝一
    • Organizer
      第69回日本めまい平衡医学会
    • Place of Presentation
      京都市
    • Related Report
      2012 Final Research Report
  • [Book] めまいの初期診療検査 血圧・脈拍・血算・血液生化学検査でわかること.ENT臨床フロンティア めまいを見分ける・治療する 内藤 泰編2012

    • Author(s)
      山崎博司
    • Publisher
      中山書店
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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