Project/Area Number |
22791717
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Plastic surgery
|
Research Institution | The University of Tokyo |
Principal Investigator |
OSHIMA Azusa 東京大学, 医学部・附属病院, 助教 (10572331)
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | マイクロサージャリー学 / 下肢リンパ浮腫 / 早期診断 / 早期治療 / 予防リンパ肝静脈吻合術 / リンパ節廓清 / ICG / 予防的リンパ肝静脈吻合術 |
Research Abstract |
Lymphedema often develops as a postoperative complication of breast and uterine cancer. Lymphadenectomy and radiation therapy increase the rate of onset of lymphedema. However, it is difficult to detect lymphedema at an early stage, often resulting in developed lymphedema at the initial visit. To address this issue, Lymphangiography using ICG dye was performed on the patients who had gynecological operation requiring pelvic lymphadenectomy. The assessment was done before and after surgery. In the result, lymphedema was shown to develop in patients with poor preoperative lymphatic flow, which could be indication for preventive LVA. And we found the ICG image showing early lymphedema in subclinical state. Based on the results, it is possible to prevent to develop lymphedema and diagnose early lymphedema.
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