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An investigation of predictive marker of bisphosphonate-related osteonecrosis of the jaw.

Research Project

Project/Area Number 22792090
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Periodontal dentistry
Research InstitutionThe University of Tokushima

Principal Investigator

MIHARA Chie  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (70403748)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords歯学 / ビスホスホネート / 顎骨壊死
Research Abstract

Osteonecrosis of the jaw(BRONJ) is well-reported side effect of bisphosphonate(BPs) use. Many researchers are trying to clarify the process of BRONJ appearance and to find a predictive marker of BRONJ. But they are not known exactly. The purpose of this investigation is to find a marker to predict BRONJ appearance by morphological analysis and biochemical analysis at process of BRONJ formation. We could not find a predictive marker of BRONJ.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (2 results)

All 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results)

  • [Journal Article] Nagata Topical and intermittent application of parathyroid hormone recovers alveolar bone loss in rat experimental periodontitis2011

    • Author(s)
      K. Tokunaga, H. Seto, H. Ohba, C. Mihara, H. Hama, M. Horibe, S. Yoneda, T.
    • Journal Title

      J Periodont Res

      Volume: 46 Issue: 6 Pages: 655-662

    • DOI

      10.1111/j.1600-0765.2011.01386.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Topical and intermittent application of parathyroid hormone recover salveolar bone loss in rat experimental periodontitis2011

    • Author(s)
      Tokunaga K, et al
    • Journal Title

      J Periodont Res

      Volume: 46 Pages: 655-652

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

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