Application of MR Fingerprinting in Pediatric Brain MRI

• Project/Area Number: 22K07746
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 52040:Radiological sciences-related
• Research Institution: Kyoto University
• Principal Investigator: 伏見 育崇 京都大学, 医学研究科, 准教授 (90639014)
• Co-Investigator(Kenkyū-buntansha): 坂田 昭彦 京都大学, 医学研究科, 助教 (10838981) ; 日野田 卓也 京都大学, 医学研究科, 客員研究員 (30885132) ; 奥知 左智 京都大学, 医学研究科, 特定助教 (30910517) ; 吉田 健司 京都大学, 医学研究科, 助教 (50790557) ; 中島 諭 京都大学, 医学研究科, 助教 (80830091) ; 横山 淳史 京都大学, 医学研究科, 助教 (90529447)
• Project Period (FY): 2022-04-01 – 2025-03-31
• Project Status: Granted (Fiscal Year 2023)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2024: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2023: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2022: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: MR Fingerprinting / 低出生体重児 / 神経皮膚黒色症 / 小児白質脳症 / T1値 / T2値 / MRI / 脳 / 定量画像 / 小児 / fingerprinting

Outline of Research at the Start

本研究では、①MRF撮影方法の最適化、②MRFの臨床的有用性の評価、③既存定量画像と組み合わせた評価、に取り組む。臨床的有用性の評価については、神経線維の髄鞘化に伴いT1値、T2値がダイナミックに変化していくことが知られている小児に着目し、(a)低出生体重児のMRFによる発達評価、(b)神経皮膚黒色症のMRFによる重症度評価、(c)小児白質脳症のMRFによる予後予測、に取組む。

Outline of Annual Research Achievements

MR fingerprinting (MRF) の登場により、緩和時定数（定量値）であるT1値、T2値の両者が簡便に取得できるようになりその臨床応用が進展するものと思われるが、その基盤的情報はいまだ不十分である。本研究の目的は、①MRF撮影方法の最適化、②MRFの臨床的有用性の評価、③既存定量画像と組み合わせた評価に取り組み、MRIによる病変診断の精緻化を加速化させることである。
① MRF撮影方法の最適化: MRFについては、試験的な技術研究は行われているが、実際の患者診療に耐えうるMRF撮影/画像処理方法の最適化は現状では十分に行われていない。本研究では、臨床現場で2Dと3DのMRF撮影を行い、定量値が既知であるファントムの撮影や、健常被験者撮影を行い、比較検討を行った。また、認知症に応用可能な新たな2D MRF撮影方法の共同研究についても積極的に取り組んでデータ収集を引き続き行った。
② MRFの臨床的有用性の評価: T1値・T2値は髄鞘やメラニンに強く影響を受ける。低出生体重児の発達評価（髄鞘形成）、神経皮膚黒色症の重症度評価（メラニン沈着）、小児白質脳症の予後予測（髄鞘崩壊）、といった臨床データの蓄積を引き続き行った。
③ 既存定量画像と組み合わせた評価： また、T1値やT2値の測定を3D QALAS法と呼ばれる手法で行い、3D-MRFと、比較検討を行った。
①、②、③について、引き続き順調に取り組めていると考えられる。

Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

① MRF撮影方法の最適化: 2023年度においては、多様なMRF撮影に取り組み、ファントム撮影や健常被験者撮影を通じて、臨床現場に即したMRF撮影を追求でき、新たな2D-MRF撮影のデータ蓄積も進めることができた。概ね順調な進展と考えられる。
② MRFの臨床的有用性の評価:低出生体重児の発達評価については良好なデータ蓄積が得られているが、引き続きデータ蓄積を進める。神経皮膚黒色症については、データ蓄積が良好のため、解析を進めている。小児白質脳症についても臨床データの蓄積を行えたが、引き続きデータ蓄積を進める。概ね順調な進展と考えられる。
③ 既存定量画像と組み合わせた評価： 初期検討のデータ整理を行っている。また、新規の定量撮影法（3D QALAS法）についてもデータ蓄積を行っている。順調な進展と考えられる。

Strategy for Future Research Activity

① MRF撮影方法の最適化: 2024年度以降も多様なMRF撮影に取り組む。
② MRFの臨床的有用性の評価:　順調な経過であり、引き続きデータ蓄積を行い、データ整理を行う。
③ 既存定量画像と組み合わせた評価： 各種定量値は① で最適化されたMRF撮影方法、新規の撮影方法が加わり、検討が複雑化しつつある。最適化の手法に既存定量値との比較も加えて検討を行う。

Research Products

• [Journal Article] Thin-slice reverse encoding distortion correction DWI facilitates visualization of non-functioning pituitary neuroendocrine tumor (PitNET)/pituitary adenoma and surrounding normal structures (2024)
  • Author(s): Ito Shuichi、Okuchi Sachi、Fushimi Yasutaka、Otani Sayo、Wicaksono Krishna Pandu、Sakata Akihiko、Miyake Kanae Kawai、Numamoto Hitomi、Nakajima Satoshi、Tagawa Hiroshi、Tanji Masahiro、Sano Noritaka、Kondo Hiroki、Imai Rimika、Saga Tsuneo、Fujimoto Koji、Arakawa Yoshiki、Nakamoto Yuji
  • Journal Title: European Radiology Experimental Volume: 8 Issue: 1
  • DOI: 10.1186/s41747-024-00430-8
  • Peer Reviewed / Open Access
• [Journal Article] Specific consistency score for rational selection of epilepsy resection surgery candidates (2024)
  • Author(s): Tojima Maya,Shimotake Akihiro,Neshige Shuichiro,Okada Tadashi,Kobayashi Katsuya,Usami Kiyohide,Matsuhashi Masao,Honda Masayuki,Takeyama Hirofumi,Hitomi Takefumi,Yoshida Takeshi,Yokoyama Atsushi,Fushimi Yasutaka,Ueno Tsukasa,Yamao Yukihiro,Kikuchi Takayuki,Namiki Takao,Arakawa Yoshiki,Takahashi Ryosuke,Ikeda Akio
  • Journal Title: Epilepsia Volume: 65 Issue: 5 Pages: 1322-1332
  • DOI: 10.1111/epi.17945
  • Peer Reviewed
• [Journal Article] Segmentation and volume estimation of habenula using deep-learning in patients with depression (2024)
  • Author(s): Kyuragi Yusuke、Oishi Naoya、Hatakoshi Momoko、Hirano Jinichi、Noda Takamasa、Yoshihara Yujiro、Ito Yuri、Igarashi Hiroyuki、Miyata Jun、Takahashi Kento、Kamiya Kei、Matsumoto Junya、Okada Tomohisa、Fushimi Yasutaka、Nakagome Kazuyuki、Mimura Masaru、Murai Toshiya、Suwa Taro
  • Journal Title: Biological Psychiatry Global Open Science Volume: - Issue: 4 Pages: 100314-100314
  • DOI: 10.1016/j.bpsgos.2024.100314
  • Peer Reviewed / Open Access
• [Journal Article] Hemosiderin Detection inside the Mammillary Bodies Using Quantitative Susceptibility Mapping on Patients with Wernicke-Korsakoff Syndrome (2024)
  • Author(s): Nakamura Yuri、Fushimi Yasutaka、Hinoda Takuya、Nakajima Satoshi、Sakata Akihiko、Okuchi Sachi、Otani Sayo、Tagawa Hiroshi、Wang Yang、Ikeda Satoshi、Kawashima Hirotsugu、Uemura Maiko T、Nakamoto Yuji
  • Journal Title: Magnetic Resonance in Medical Sciences Volume: 23 Issue: 1 Pages: 14-17
  • DOI: 10.2463/mrms.ici.2022-0109
  • ISSN: 1347-3182, 1880-2206
  • Peer Reviewed / Open Access
• [Journal Article] Vessel wall imaging and carotid artery stenting for recurrent cervical internal carotid artery vasospasm syndrome: illustrative case (2023)
  • Author(s): Tokunaga Shinya、Yamao Yukihiro、Maki Takakuni、Ishii Akira、Miyake Tomoaki、Yasuda Ken、Abekura Yu、Okawa Masakazu、Kikuchi Takayuki、Fushimi Yasutaka、Yoshida Kazumichi、Miyamoto Susumu
  • Journal Title: Journal of Neurosurgery: Case Lessons Volume: 5 Issue: 23
  • DOI: 10.3171/case2341
  • Peer Reviewed / Open Access
• [Journal Article] Association between enhanced carbonyl stress and decreased apparent axonal density in schizophrenia by multimodal white matter imaging (2023)
  • Author(s): Son Shuraku、Arai Makoto、Toriumi Kazuya、Andica Christina、Matsuyoshi Daisuke、Kamagata Koji、Aoki Shigeki、Kawashima Takahiko、Kochiyama Takanori、Okada Tomohisa、Fushimi Yasutaka、Nakamoto Yuji、Kobayashi Yuko、Murai Toshiya、Itokawa Masanari、Miyata Jun
  • Journal Title: Scientific Reports Volume: 13 Issue: 1 Pages: 12220-12220
  • DOI: 10.1038/s41598-023-39379-w
  • Peer Reviewed / Open Access
• [Journal Article] From pituitary adenoma to PitNET: it is time to discuss PitNET/pituitary adenoma (2023)
  • Author(s): Fushimi Yasutaka、Taoka Toshiaki、Naganawa Shinji
  • Journal Title: Japanese Journal of Radiology Volume: 41 Issue: 8 Pages: 787-788
  • DOI: 10.1007/s11604-023-01412-3
  • Peer Reviewed / Open Access
• [Journal Article] Can we distinguish atypical primary brain lymphoma from glioblastoma multiforme by looking at the non-enhancing tumor? (2023)
  • Author(s): Fushimi Yasutaka、Nakajima Satoshi
  • Journal Title: European Radiology Volume: 33 Issue: 8 Pages: 5355-5356
  • DOI: 10.1007/s00330-023-09750-6
  • Peer Reviewed
• [Journal Article] Value of Quantitative Susceptibility Mapping in Clinical Neuroradiology (2023)
  • Author(s): Fushimi Yasutaka、Nakajima Satoshi、Sakata Akihiko、Okuchi Sachi、Otani Sayo、Nakamoto Yuji
  • Journal Title: Journal of Magnetic Resonance Imaging Volume: - Issue: 6 Pages: 1914-1929
  • DOI: 10.1002/jmri.29010
  • Peer Reviewed
• [Journal Article] Incidence of neurocutaneous melanosis in Japanese pediatric patients with congenital melanocytic nevi (2023)
  • Author(s): Takiya Miyuki、Fushimi Yasutaka、Sakamoto Michiharu、Yoshida Takeshi、Ueno Kentaro、Nakajima Satoshi、Sakata Akihiko、Okuchi Sachi、Otani Sayo、Tagawa Hiroshi、Morimoto Naoki、Nakamoto Yuji
  • Journal Title: Scientific Reports Volume: 13 Issue: 1
  • DOI: 10.1038/s41598-023-43829-w
  • Peer Reviewed / Open Access
• [Journal Article] Continuous and Early Progression of Carotid Intima-Media Thickness after Radiotherapy for Head and Neck Cancer: 5-Year Prospective Observational Study (2023)
  • Author(s): Yamamoto Y, Okawa M, Suzuki K, Tateya I, Yoshimura M, Fushimi Y, Kato ET, Yoshida K, Miyamoto S.
  • Journal Title: Cerebrovasc Dis Volume: 30 Issue: 5 Pages: 543-551
  • DOI: 10.1159/000528622
  • Peer Reviewed
• [Journal Article] Partially thrombosed giant basilar artery aneurysm with attenuated contrast enhancement of the intraluminal thrombus on vessel wall MRI after flow diversion treatment: illustrative case (2023)
  • Author(s): Matsukawa So、Ishii Akira、Fushimi Yasutaka、Abekura Yu、Nagahori Takashi、Kikuchi Takayuki、Okawa Masakazu、Yamao Yukihiro、Sasaki Natsuhi、Tsuji Hirofumi、Akiyama Ryo、Miyamoto Susumu
  • Journal Title: Journal of Neurosurgery: Case Lessons Volume: 6 Issue: 14
  • DOI: 10.3171/case23307
  • Peer Reviewed / Open Access
• [Journal Article] Vessel wall MRI in moyamoya disease: arterial wall enhancement varies depending on age, arteries, and disease progression (2023)
  • Author(s): Tagawa Hiroshi、Fushimi Yasutaka、Funaki Takeshi、Nakajima Satoshi、Sakata Akihiko、Okuchi Sachi、Hinoda Takuya、Grinstead John、Ahn Sinyeob、Hidaka Yu、Yoshida Kazumichi、Miyamoto Susumu、Nakamoto Yuji
  • Journal Title: European Radiology Volume: 34 Issue: 4 Pages: 2183-2194
  • DOI: 10.1007/s00330-023-10251-9
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Evaluation of isocitrate dehydrogenase mutation in 2021 world health organization classification grade 3 and 4 glioma adult-type diffuse gliomas with 18F-fluoromisonidazole PET (2023)
  • Author(s): Wang Yang、Fushimi Yasutaka、Arakawa Yoshiki、Shimizu Yoichi、Sano Kohei、Sakata Akihiko、Nakajima Satoshi、Okuchi Sachi、Hinoda Takuya、Oshima Sonoko、Otani Sayo、Ishimori Takayoshi、Tanji Masahiro、Mineharu Yohei、Yoshida Kazumichi、Nakamoto Yuji
  • Journal Title: Japanese Journal of Radiology Volume: 41 Issue: 11 Pages: 1255-1264
  • DOI: 10.1007/s11604-023-01450-x
  • Peer Reviewed / Open Access
• [Journal Article] Denoising approach with deep learning-based reconstruction for neuromelanin-sensitive MRI: image quality and diagnostic performance (2023)
  • Author(s): Oshima Sonoko、Fushimi Yasutaka、Miyake Kanae Kawai、Nakajima Satoshi、Sakata Akihiko、Okuchi Sachi、Hinoda Takuya、Otani Sayo、Numamoto Hitomi、Fujimoto Koji、Shima Atsushi、Nambu Masahito、Sawamoto Nobukatsu、Takahashi Ryosuke、Ueno Kentaro、Saga Tsuneo、Nakamoto Yuji
  • Journal Title: Japanese Journal of Radiology Volume: 41 Issue: 11 Pages: 1216-1225
  • DOI: 10.1007/s11604-023-01452-9
  • Peer Reviewed / Open Access
• [Journal Article] “Transcallosal” periventricular anastomosis in moyamoya disease: the fourth periventricular anastomosis and a potential predictor of hemorrhage (2023)
  • Author(s): Yamao Yukihiro、Funaki Takeshi、Yamada Hiroki、Okawa Masakazu、Mineharu Yohei、Kikuchi Takayuki、Fushimi Yasutaka、Kataoka Hiroharu、Yoshida Kazumichi、Takahashi Jun C、Miyamoto Susumu、Arakawa Yoshiki
  • Journal Title: Journal of Stroke and Cerebrovascular Diseases Volume: 32 Issue: 12 Pages: 107428-107428
  • DOI: 10.1016/j.jstrokecerebrovasdis.2023.107428
  • Peer Reviewed
• [Journal Article] Ruptured thrombosed vertebral artery dissecting aneurysm treated with staged flow diverter after prediction of the rupture point by vessel wall MRI (2023)
  • Author(s): Matsukawa So、Ishii Akira、Fushimi Yasutaka、Terada Yukinori、Natsuhara Hiroki、Kikuchi Takayuki、Okawa Masakazu、Yamao Yukihiro、Abekura Yu、Sasaki Natsuhi、Tsuji Hirofumi、Akiyama Ryo、Miyamoto Susumu、Arakawa Yoshiki
  • Journal Title: The Neuroradiology Journal Volume: - Issue: 6 Pages: 772-775
  • DOI: 10.1177/19714009231224420
  • Peer Reviewed
• [Journal Article] Telomerase reverse transcriptase promoter mutation and histologic grade in IDH wild-type histological lower-grade gliomas: The value of perfusion-weighted image, diffusion-weighted image, and 18F-FDG-PET (2023)
  • Author(s): Ikeda Satoshi、Sakata Akihiko、Fushimi Yasutaka、Okuchi Sachi、Arakawa Yoshiki、Makino Yasuhide、Mineharu Yohei、Nakajima Satoshi、Hinoda Takuya、Yoshida Kazumichi、Miyamoto Susumu、Nakamoto Yuji
  • Journal Title: European Journal of Radiology Volume: 159 Pages: 110658-110658
  • DOI: 10.1016/j.ejrad.2022.110658
  • Peer Reviewed
• [Journal Article] Information flow and dynamic functional connectivity during electroconvulsive therapy in patients with depression. (2023)
  • Author(s): Kyuragi Y, *Oishi N, Yamasaki S, Hazama M, Miyata J, Shibata M, Fujiwara H, Fushimi Y, Murai T, Suwa T.
  • Journal Title: J Affect Disord. Volume: 328 Pages: 141-152
  • DOI: 10.1016/j.jad.2023.02.060
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of apparent diffusion coefficient of two-dimensional BLADE turbo gradient- and spin-echo diffusion-weighted imaging with a breast phantom (2023)
  • Author(s): Ohki Akiko、Sagawa Hajime、Iima Mami、Kataoka Masako、Fushimi Yasutaka、Zhou Kun
  • Journal Title: Radiological Physics and Technology Volume: 16 Issue: 1 Pages: 118-126
  • DOI: 10.1007/s12194-022-00694-y
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Brain imaging of sequential acquisition using a flexible PET scanner and 3-T MRI: quantitative and qualitative assessment (2022)
  • Author(s): Nakajima Satoshi、Fushimi Yasutaka、Hinoda Takuya、Sakata Akihiko、Okuchi Sachi、Arakawa Yoshiki、Ishimori Takayoshi、Nakamoto Yuji
  • Journal Title: Annals of Nuclear Medicine Volume: 37 Issue: 4 Pages: 209-218
  • DOI: 10.1007/s12149-022-01817-6
  • Peer Reviewed
• [Journal Article] Accuracy, repeatability, and reproducibility of T1 and T2 relaxation times measurement by 3D magnetic resonance fingerprinting with different dictionary resolutions (2022)
  • Author(s): Wicaksono Krishna Pandu、Fushimi Yasutaka、Nakajima Satoshi、Sakata Akihiko、Okuchi Sachi、Hinoda Takuya、Oshima Sonoko、Otani Sayo、Tagawa Hiroshi、Urushibata Yuta、Nakamoto Yuji
  • Journal Title: European Radiology Volume: 33 Issue: 4 Pages: 2895-2904
  • DOI: 10.1007/s00330-022-09244-x
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of deep gray matter for early brain development using quantitative susceptibility mapping (2022)
  • Author(s): Otani Sayo、Fushimi Yasutaka、Iwanaga Kogoro、Tomotaki Seiichi、Shimotsuma Taiki、Nakajima Satoshi、Sakata Akihiko、Okuchi Sachi、Hinoda Takuya、Wicaksono Krishna Pandu、Takita Junko、Kawai Masahiko、Nakamoto Yuji
  • Journal Title: European Radiology Volume: - Issue: 6 Pages: 4488-4499
  • DOI: 10.1007/s00330-022-09267-4
  • Peer Reviewed
• [Journal Article] Comparison of TGSE-BLADE DWI, RESOLVE DWI, and SS-EPI DWI in healthy volunteers and patients after cerebral aneurysm clipping (2022)
  • Author(s): Okuchi Sachi、Fushimi Yasutaka、Yoshida Kazumichi、Nakajima Satoshi、Sakata Akihiko、Hinoda Takuya、Otani Sayo、Sagawa Hajime、Zhou Kun、Yamao Yukihiro、Okawa Masakazu、Nakamoto Yuji
  • Journal Title: Scientific Reports Volume: 12 Issue: 1 Pages: 17689-17689
  • DOI: 10.1038/s41598-022-22760-6
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Super-resolution application of generative adversarial network on brain time-of-flight MR angiography: image quality and diagnostic utility evaluation (2022)
  • Author(s): Wicaksono Krishna Pandu、Fujimoto Koji、Fushimi Yasutaka、Sakata Akihiko、Okuchi Sachi、Hinoda Takuya、Nakajima Satoshi、Yamao Yukihiro、Yoshida Kazumichi、Miyake Kanae Kawai、Numamoto Hitomi、Saga Tsuneo、Nakamoto Yuji
  • Journal Title: European Radiology Volume: 33 Issue: 2 Pages: 936-946
  • DOI: 10.1007/s00330-022-09103-9
  • Peer Reviewed
• [Presentation] 先天性色素細胞性色素性母斑患者における神経皮膚黒色素症の合併率 (2024)
  • Author(s): 伏見育崇、瀧谷幸、中島諭、坂田昭彦、奥知左智、大谷紗代、田川弘、汪洋、櫻間梓、池田賢司、伊藤秀一、梅花優貴、馬永萍、中本裕士。
  • Organizer: 第53回日本神経放射線学会
• [Presentation] 下垂体腺腫患者におけるAiCEによりノイズ除去を行った短時間撮像RDC-DWIの画像評価 (2024)
  • Author(s): 奥知左智、伏見育崇、藤本晃司、三宅可奈江、伊藤秀一、中島諭、坂田昭彦、大谷紗代、沼元瞳、門前侑一郎、近藤大貴、今井里実華、中本裕士
  • Organizer: 第53回日本神経放射線学会
• [Presentation] Inter-scanner consistency of T1 map and proton spin density map derived from strategically acquired gradient echo (STAGE) imaging. (2023)
  • Author(s): Yasutaka Fushimi, Satoshi Nakajima, Sachi Okuchi, Akihiko Sakata, Takuya Hinoda, Sayo Otani, Azusa Sakurama, Krishna Pandu Wicaksono, Hiroshi Tagawa, Yang Wang, Satoshi Ikeda, Shuichi Ito, Miyuki Takiya, and Yuji Nakamoto.
  • Organizer: The ISMRM & ISMRT 2023 Annual Meeting & Exhibition in Toronto
  • Int'l Joint Research
• [Presentation] Evaluation of reverse encoding distortion correction DWI in patients with non-functioning pituitary macroadenoma. (2023)
  • Author(s): Shuichi Ito, Sachi Okuchi, Yasutaka Fushimi, Kanae Kawai Miyake, Koji Fujimoto, Hitomi Numamoto, Satoshi Nakajima, Akihiko Sakata,Takuya Hinoda, Sayo Otani, Azusa Sakurama, Krishna Pandu Wicaksono, Hiroshi Tagawa, Yang Wang, Satoshi Ikeda, Miyuki Takiya, Hiroki Kondo, Rimika Imai, Tsuneo Saga, and Yuji Nakamoto
  • Organizer: The ISMRM & ISMRT 2023 Annual Meeting & Exhibition in Toronto
  • Int'l Joint Research
• [Presentation] Application of slice-accelerated one-minute TGSE-BLADE DWI in clinical practices. (2023)
  • Author(s): Sachi Okuchi, Yasutaka Fushimi, Satoshi Nakajima, Akihiko Sakata, Takuya Hinoda, Sayo Otani, Azusa Sakurama, Krishna Pandu Wicaksono, Hiroshi Tagawa, Yang Wang, Satoshi Ikeda, Shuichi ito, Miyuki Takiya, Kun Zhou, and Yuji Nakamoto.
  • Organizer: The ISMRM & ISMRT 2023 Annual Meeting & Exhibition in Toronto
  • Int'l Joint Research
• [Presentation] Strategically Acquired Gradient Echo (STAGE) 法で得られる定量値の装置間における検討 (2023)
  • Author(s): 伏見育崇、中島諭、坂田昭彦、奥知左智、大谷紗代、田川弘、汪洋、櫻間梓、池田賢司、伊藤秀一、瀧谷幸、梅花優貴、馬永萍、中本裕士
  • Organizer: 第51回日本磁気共鳴医学会大会
• [Presentation] Denoising approach with deep learning-based reconstruction for neuromelanin-sensitive MRI. (2022)
  • Author(s): Sonoko Oshima, Yasutaka Fushimi, Kanae Kawai Miyake, Satoshi Nakajima, Akihiko Sakata, Sachi Okuchi, Takuya Hinoda, Sayo Otani, Hitomi Numamoto, Masahito Nambu, Koji Fujimoto, Tsuneo Saga, Yuji Nakamoto.
  • Organizer: The 108th Scientific Assembly and Annual Meeting of the Radiological Society of North America.
  • Int'l Joint Research
• [Presentation] Comparison of DWIs after cerebral aneurysmal clipping between TGSE-BLADE-DWI, RESOLVE and SS-EPI. (2022)
  • Author(s): Sachi Okuchi, Yasutaka Fushimi, Satoshi Nakajima, Akihiko Sakata, Takuya Hinoda, Sayo Otani, Azusa Sakurama, Krishna Pandu Wicaksono, Hiroshi Tagawa, Yang Wang, Satoshi Ikeda, Kun Zhou, Yuji Nakamoto.
  • Organizer: International Society for Magnetic Resonance in Medicine
  • Int'l Joint Research
• [Presentation] Correlation between SUV, tumor blood flow and ADC of extra-axial tumors on FDG-PET/MRI. (2022)
  • Author(s): Sayo Otani, Yasutaka Fushimi, Satoshi Nakajima, Akihiko Sakata, Sachi Okuchi, Takuya Hinoda, Azusa Sakurama, Krishna Pandu Wicaksono, Hiroshi Tagawa, Yang Wang, Satoshi Ikeda, Yuji Nakamoto.
  • Organizer: International Society for Magnetic Resonance in Medicine
  • Int'l Joint Research
• [Presentation] もやもや病に対する DANTE-T1-SPACE を用いた血管壁イメージング (2022)
  • Author(s): 田川弘、伏見育崇、中島諭、坂田昭彦、奥知左智、日野田卓也、John Grinstead, Sinyeob Ahn, 中本裕士
  • Organizer: 第81回日本医学放射線学会総会
• [Presentation] GANによる脳MRA画像の高分解能画像化 (2022)
  • Author(s): Krishna Pandu Wicaksono、藤本晃司、伏見育崇、坂田昭彦、日野田卓也、三宅可奈江、沼元瞳、佐賀恒夫、中本裕士
  • Organizer: 第81回日本医学放射線学会総会