| Project/Area Number |
22K20522
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Multi-year Fund |
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| Review Section |
0501:Physical chemistry, functional solid state chemistry, organic chemistry, polymers, organic materials, biomolecular chemistry, and related fields
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| Research Institution | Hokkaido University |
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Principal Investigator |
Huang Chung-Yang 北海道大学, 化学反応創成研究拠点, 准教授 (90956153)
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| Project Period (FY) |
2022-08-31 – 2024-03-31
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| Project Status |
Completed (Fiscal Year 2023)
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| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2023: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2022: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | indigo / photoswitch / organic synthesis / metal catalyst / data science / photochemistry / metal catalysis |
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| Outline of Research at the Start |
Indigo is one of the most abundant dyes used in daily life, and their derivatives show interesting photochemical properties when irradiated with red light. This research project aims to develop efficient synthetic methods to functionalize indigo dye as red-light responsive molecules.
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| Outline of Final Research Achievements |
In this project, we have made significant progress in promoting the use of indigo compounds as photoresponsive molecular tools. We first developed a new copper-catalyzed direct functionalization of indigo dye to build new red-light photoswitches. Computational studies and data science approaches have provided insight on reaction mechanism and structure-property relationships. We have also successfully implemented the first example of indigo photoswitches in thin films, which demonstrates its potential in material science. Additionally, we have prepared a review to summarize the history and perspectives of utilizing indigos as photoresponsive molecular tools. Overall, this project will yield three publications and has pointed out new directions for indigo chemistry.
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| Academic Significance and Societal Importance of the Research Achievements |
Due to their red-light absorbance, indigo derivatives are expected to be useful in biomedicine and material science. This research has demonstrated their potential as photoresponsive molecular tools by developing new synthetic methods and building structure-property relationships.
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